SG ID

SG00000059 

UniProt Accession

Q7YWU9_CAEEL;Q7YWU9;  

Theoretical PI

8.33  

Molecular Weight

20128 Da  

Genbank Nucleotide ID

Z48809;  

Genbank Protein ID

CAE17928.1; 

Gene Name

ubxn-5 

Gene Synonyms/Alias

ORFNames=CELE_T01E8.9 

Protein Name

 

Protein Synonyms/Alias

SubName: Protein UBXN-5 

Caenorhabditis elegans 

6239 

Temporarily unavailable 

The information of related literatures

1. S. Yamauchi, Y. Sasagawa, T. Ogura and K. Yamanaka (2007) Differential expression pattern of UBX family genes in Caenorhabditis elegans. Biochem Biophys Res Commun 358(2): 545-52. 

Abstract
UBX (ubiquitin regulatory X)-containing proteins belong to an evolutionary conserved protein family and determine the specificity of p97/VCP/Cdc48p function by binding as its adaptors. Caenorhabditis elegans was found to possess six UBX-containing proteins, named UBXN-1 to -6. However, no general or specific function of them has been revealed. During the course of understanding not only their function but also specified function of p97, we investigated spatial and temporal expression patterns of six ubxn genes in this study. Transcript analyses showed that the expression pattern of each ubxn gene was different throughout worm's development and may show potential developmental dynamics in their function, especially ubxn-5 was expressed specifically in the spermatogenic germline, suggesting a crucial role in spermatogenesis. In addition, as ubxn-4 expression was induced by ER stress, it would function as an ERAD factor in C. elegans. In vivo expression analysis by using GFP translational fusion constructs revealed that six ubxn genes show distinct expression patterns. These results altogether demonstrate that the expression of all six ubxn genes of C. elegans is differently regulated. PMID: [17498661] 

Figures for illustrating the function of this protein/gene

Function

 

Subcellular Location

 

Tissue Specificity

 

Gene Ontology

GO ID

GO term

Evidence

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Interpro

IPR001012;    UBX.
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Pfam

PF00789;    UBX;    1.
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SMART

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PROSITE

PS50033;    UBX;    1.
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PRINTS

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Created Date

18-Oct-2012 

Record Type

Experiment identified 

Protein sequence Annotation

Nucleotide Sequence

Length: 38128 bp   Go to nucleotide: FASTA

Protein Sequence

Length: 174 bp   Go to amino acid: FASTA

The verified Protein-Protein interaction information

UniProt

Gene Symbol

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Other Protein-Protein interaction resources

String database  

UniProt

Gene Symbol

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View Microarray data

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