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SG ID
SG00000072 
UniProt Accession
 
Theoretical PI
-  
Molecular Weight
Da  
Genbank Nucleotide ID
 
Genbank Protein ID
 
Gene Name
 
Gene Synonyms/Alias
 
Protein Name
 
Protein Synonyms/Alias
 
Organism
 
NCBI Taxonomy ID
 
Chromosome Location
chr:I;3158516-3162378;-1
View in Ensembl genome browser  
Function in Stage
Function in Cell Type
Description
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The information of related literatures
1. L. S. Salinas, E. Maldonado, M. Macias-Silva, T. K. Blackwell and R. E. Navarro (2007) The DEAD box RNA helicase VBH-1 is required for germ cell function in C. elegans. Genesis 45(9): 533-46. 

Abstract
Vasa and Belle are conserved DEAD box RNA helicases required for germ cell function. Homologs of this group of proteins in several species, including mammals, are able to complement a mutation in yeast (DED1) suggesting that their function is highly conserved. It has been proposed that these proteins are required for mRNA translation regulation, but their specific mechanism of action is still unknown. Here we describe functions of VBH-1, a C. elegans protein closely related to Belle and Vasa. VBH-1 is expressed specifically in the C. elegans germline, where it is associated with P granules, the C. elegans germ plasm counterpart. vbh-1(RNAi) animals produce fewer offspring than wild type because of defects in oocyte and sperm production, and embryonic lethality. We also find that VBH-1 participates in the sperm/oocyte switch in the hermaphrodite gonad. We conclude that VBH-1 and its orthologs may perform conserved roles in fertility and development. PMID: [17868112] 

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Function
 
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Subcellular Location
 
Tissue Specificity
 
Gene Ontology
GO IDGO termEvidence
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Interpro
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Created Date
18-Oct-2012 
Record Type
Experiment identified 
Protein sequence Annotation
Nucleotide Sequence
Length: bp   Go to nucleotide: FASTA
Protein Sequence
Length: bp   Go to amino acid: FASTA
The verified Protein-Protein interaction information
UniProt
Gene Symbol Ref Databases
Other Protein-Protein interaction resources
String database  
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