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SG ID
SG00000079 
UniProt Accession
 
Theoretical PI
-  
Molecular Weight
Da  
Genbank Nucleotide ID
 
Genbank Protein ID
 
Gene Name
 
Gene Synonyms/Alias
 
Protein Name
 
Protein Synonyms/Alias
 
Organism
 
NCBI Taxonomy ID
 
Chromosome Location
chr:III;9887123-9891349;-1
View in Ensembl genome browser  
Function in Stage
Function in Cell Type
Description
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The information of related literatures
1. C. C. Conine, P. J. Batista, W. Gu, J. M. Claycomb, D. A. Chaves, M. Shirayama and C. C. Mello (2010) Argonautes ALG-3 and ALG-4 are required for spermatogenesis-specific 26G-RNAs and thermotolerant sperm in Caenorhabditis elegans. Proc Natl Acad Sci U S A 107(8): 3588-93. 

Abstract
Gametogenesis is a thermosensitive process in numerous metazoans, ranging from worms to man. In Caenorhabditis elegans, a variety of RNA-binding proteins that associate with germ-line nuage (P granules), including the Piwi-clade argonaute PRG-1, have been implicated in maintaining fertility at elevated temperature. Here we describe the role of two AGO-class paralogs, alg-3 (T22B3.2) and alg-4 (ZK757.3), in promoting thermotolerant male fertility. A rescuing GFP PMID: [20133686] 

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Figures for illustrating the function of this protein/gene
Ref: C. C. Conine, P. J. Batista, W. Gu, J. M. Claycomb, D. A. Chaves, M. Shirayama and C. C. Mello (2010) Argonautes ALG-3 and ALG-4 are required for spermatogenesis-specific 26G-RNAs and thermotolerant sperm in Caenorhabditis elegans. Proc Natl Acad Sci U S A 107(8): 3588-93. PMID: [20133686]
Ref: C. C. Conine, P. J. Batista, W. Gu, J. M. Claycomb, D. A. Chaves, M. Shirayama and C. C. Mello (2010) Argonautes ALG-3 and ALG-4 are required for spermatogenesis-specific 26G-RNAs and thermotolerant sperm in Caenorhabditis elegans. Proc Natl Acad Sci U S A 107(8): 3588-93. PMID: [20133686]
Function
 
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Subcellular Location
 
Tissue Specificity
 
Gene Ontology
GO IDGO termEvidence
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Interpro
Pfam
SMART
PROSITE
PRINTS
Created Date
18-Oct-2012 
Record Type
Experiment identified 
Protein sequence Annotation
Nucleotide Sequence
Length: bp   Go to nucleotide: FASTA
Protein Sequence
Length: bp   Go to amino acid: FASTA
The verified Protein-Protein interaction information
UniProt
Gene Symbol Ref Databases
Other Protein-Protein interaction resources
String database  
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