Tag Content
SG ID
SG00000117 
UniProt Accession
Theoretical PI
9.44  
Molecular Weight
25698 Da  
Genbank Nucleotide ID
Genbank Protein ID
Gene Name
spata4 
Gene Synonyms/Alias
SPATA4 
Protein Name
 
Protein Synonyms/Alias
SubName: Spermatogenesis associated 4SubName: Uncharacterized protein 
Organism
Danio rerio (Zebrafish) (Brachydanio rerio) 
NCBI Taxonomy ID
7955 
Chromosome Location
chr:14;37614213-37618235;-1
View in Ensembl genome browser  
Function in Stage
Function in Cell Type
Description
Temporarily unavailable 
The information of related literatures
1. S. Liu, B. Liu, S. He, Y. Zhao and Z. Wang (2005) Cloning and characterization of zebra fish SPATA4 gene and analysis of its gonad specific expression. Biochemistry (Mosc) 70(6): 638-44. 

Abstract
The spermatogenesis associated 4 gene (SPATA4, previously named TSARG2) was first cloned in human tissues and was reported to be a candidate spermatocyte apoptosis-related gene that is expressed specifically in testis. Analysis of SPATA4 expression and regulation in zebra fish may provide insight into the understanding of the complicated process of gonadogenesis. In this study, we cloned and characterized the SPATA4 gene from zebra fish (Danio rerio), which is homologous to human and mouse SPATA4. Zebra fish SPATA4 consists of six exons separated by five introns, as all SPATA4 genes in vertebrates. A promoter region was predicted using homologous blast and cloned for further study, and possible transcription factors were analyzed in this region. The putative protein encoded by this gene was analyzed using bioinformatics methods. Multi-tissue RT-PCR results demonstrated that the zebra fish SPATA4 gene is expressed specifically in testis and slightly in ovary. Analysis of the SPATA4 sequence and its spatial expression pattern indicate that this gene is highly conserved and may play an important role in the process of zebra fish gonadogenesis. PMID: [16038605] 

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Figures for illustrating the function of this protein/gene
Function
 
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Subcellular Location
 
Tissue Specificity
 
Gene Ontology
GO IDGO termEvidence
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Interpro
IPR010441;    DUF1042.
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Pfam
PF06294;    DUF1042;    1.
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SMART
PROSITE
PRINTS
Created Date
18-Oct-2012 
Record Type
Experiment identified 
Protein sequence Annotation
Nucleotide Sequence
Length: bp   Go to nucleotide: FASTA
Protein Sequence
Length: 224 bp   Go to amino acid: FASTA
The verified Protein-Protein interaction information
UniProt
Gene Symbol Ref Databases
Other Protein-Protein interaction resources
String database  
View Microarray data
Temporarily unavailable 
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