SG ID

SG00000177 

UniProt Accession

Q9BKJ2_DROME;Q9BKJ2;Q8IRJ1;  

Theoretical PI

6.48  

Molecular Weight

147244 Da  

Genbank Nucleotide ID

AF242375; AE014296;  

Genbank Protein ID

AAK27793.2; AAN11438.1; 

Gene Name

fwd 

Gene Synonyms/Alias

ORFNames=CG7004, Dmel_CG7004 

Protein Name

 

Protein Synonyms/Alias

SubName: Four wheel drive, isoform CEC=2.7.1.67SubName: Phosphatidylinositol 4-kinase beta isoform 

Drosophila melanogaster (Fruit fly) 

7227 

Temporarily unavailable 

The information of related literatures

1. J. A. Brill, G. R. Hime, M. Scharer-Schuksz and M. T. Fuller (2000) A phospholipid kinase regulates actin organization and intercellular bridge formation during germline cytokinesis. Development 127(17): 3855-64. 

Abstract
The endgame of cytokinesis can follow one of two pathways depending on developmental context PMID: [10934029] 

Figures for illustrating the function of this protein/gene

Function

 

Subcellular Location

 

Tissue Specificity

 

Gene Ontology

GO ID	GO term	Evidence
GO:0004430	F:1-phosphatidylinositol 4-kinase activity	NAS:FlyBase.
GO:0000916	P:actomyosin contractile ring contraction	IMP:FlyBase.
GO:0007110	P:cytokinesis after meiosis I	IMP:FlyBase.
GO:0007111	P:cytokinesis after meiosis II	IMP:FlyBase.
GO:0008340	P:determination of adult lifespan	IMP:FlyBase.
GO:0030726	P:male germline ring canal formation	IMP:FlyBase.
GO:0007112	P:male meiosis cytokinesis	IMP:FlyBase.
GO:0043147	P:meiotic spindle stabilization	IMP:FlyBase.
GO:0048015	P:phosphatidylinositol-mediated signaling	IEA:InterPro.
GO:0048137	P:spermatocyte division	IMP:FlyBase.

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Interpro

IPR011009;    Kinase-like_dom.
IPR000403;    PI3/4_kinase_cat_dom.
IPR018936;    PI3/4_kinase_CS.
IPR015433;    PI_Kinase.
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Pfam

PF00454;    PI3_PI4_kinase;    1.
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SMART

SM00146;    PI3Kc;    1.
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PROSITE

PS00915;    PI3_4_KINASE_1;    1.
PS00916;    PI3_4_KINASE_2;    1.
PS50290;    PI3_4_KINASE_3;    1.
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PRINTS

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Created Date

18-Oct-2012 

Record Type

Experiment identified 

Protein sequence Annotation

Nucleotide Sequence

Length: 4464 bp   Go to nucleotide: FASTA

Protein Sequence

Length: 1338 bp   Go to amino acid: FASTA

The verified Protein-Protein interaction information

UniProt	Gene Symbol	Ref Databases
CI_DROME	ci	BioGRID
O77135_DROME	spn-B	BioGRID

Other Protein-Protein interaction resources

String database  

UniProt

Gene Symbol

Ref Databases

View Microarray data

Temporarily unavailable 

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