SG ID

SG00000381 

UniProt Accession

F6SK35_HORSE;F6SK35;  

Theoretical PI

9  

Molecular Weight

43118 Da  

Genbank Nucleotide ID

 

Genbank Protein ID

 

Gene Name

CX43 

Gene Synonyms/Alias

 

Protein Name

Gap junction protein 

Protein Synonyms/Alias

 

Equus caballus (Horse) 

9796 

Temporarily unavailable 

The information of related literatures

1. A. Hejmej, M. Kotula-Balak, J. Sadowska and B. Bilinska (2007) Expression of connexin 43 protein in testes, epididymides and prostates of stallions. Equine Vet J 39(2): 122-7. 

Abstract
REASONS FOR PERFORMING STUDY PMID: [17378440] 

Figures for illustrating the function of this protein/gene

Function

One gap junction consists of a cluster of closely packedpairs of transmembrane channels, the connexons, through whichmaterials of low MW diffuse from one cell to a neighboring cell(By similarity). 

Subcellular Location

Membrane; Multi-pass membrane protein (Bysimilarity). 

Tissue Specificity

 

Gene Ontology

GO ID	GO term	Evidence
GO:0005922	C:connexon complex	IEA:InterPro.
GO:0043292	C:contractile fiber	IEA:Compara.
GO:0005829	C:cytosol	IEA:Compara.
GO:0005916	C:fascia adherens	IEA:Compara.
GO:0016021	C:integral to membrane	IEA:UniProtKB-KW.
GO:0005243	F:gap junction channel activity	IEA:Compara.
GO:0004871	F:signal transducer activity	IEA:Compara.
GO:0007512	P:adult heart development	IEA:Compara.
GO:0006915	P:apoptotic process	IEA:Compara.
GO:0048514	P:blood vessel morphogenesis	IEA:Compara.
GO:0007267	P:cell-cell signaling	IEA:Compara.
GO:0002070	P:epithelial cell maturation	IEA:Compara.
GO:0001947	P:heart looping	IEA:Compara.
GO:0001701	P:in utero embryonic development	IEA:Compara.
GO:0060174	P:limb bud formation	IEA:Compara.
GO:0010629	P:negative regulation of gene expression	IEA:Compara.
GO:0001764	P:neuron migration	IEA:Compara.
GO:0010628	P:positive regulation of gene expression	IEA:Compara.
GO:0043123	P:positive regulation of I-kappaB kinase/NF-kappaB cascade	IEA:Compara.
GO:0045844	P:positive regulation of striated muscle tissue development	IEA:Compara.
GO:0008016	P:regulation of heart contraction	IEA:Compara.
GO:0043403	P:skeletal muscle tissue regeneration	IEA:Compara.
GO:0055085	P:transmembrane transport	IEA:GOC.

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Interpro

IPR000500;    Connexin.
IPR002261;    Connexin43.
IPR013124;    Connexin43_C.
IPR019570;    Connexin_CCC.
IPR017990;    Connexin_CS.
IPR013092;    Connexin_N.
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Pfam

PF00029;    Connexin;    1.
PF03508;    Connexin43;    1.
PF10582;    Connexin_CCC;    1.
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SMART

SM00037;    CNX;    1.
SM01089;    Connexin_CCC;    1.
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PROSITE

PS00407;    CONNEXINS_1;    1.
PS00408;    CONNEXINS_2;    1.
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PRINTS

PR00206;    CONNEXIN.;   
PR01132;    CONNEXINA1.;   
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Created Date

18-Oct-2012 

Record Type

Experiment identified 

Protein sequence Annotation

Nucleotide Sequence

Length: bp   Go to nucleotide: FASTA

Protein Sequence

Length: 382 bp   Go to amino acid: FASTA

The verified Protein-Protein interaction information

UniProt

Gene Symbol

Ref Databases

Other Protein-Protein interaction resources

String database  

UniProt

Gene Symbol

Ref Databases

View Microarray data

Temporarily unavailable 

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