It has been mapped by polymerase chain reaction on a panel of somatic cell hybrids and by fluorescence in situ hybridization to chromosome 2q11.2.
The information of related literatures
1. M. H. Modarressi, J. Cameron, K. E. Taylor and J. Wolfe (2001) Identification and characterisation of a novel gene, TSGA10, expressed in testis. Gene 262(1-2): 249-55.
Abstract We describe the isolation of a novel gene, TSGA10, by differential mRNA display which is expressed solely in adult human testis. It seems likely that the gene is expressed during spermatogenesis possibly in spermatocytes. The gene is composed of 19 exons extending over more than 80 kb. The complete cDNA contains an open reading frame of 2094 nucleotides, which appears to encode a novel protein. It has been mapped by polymerase chain reaction on a panel of somatic cell hybrids and by fluorescence in situ hybridization to chromosome 2q11.2. PMID: [11179690]
Cytoplasm (By similarity). Nucleus (Bysimilarity). Nucleus membrane (By similarity). Note=The 27 kDapeptide associates with the fibrous sheath in mature spermatozoaand localizes to the principal piece of sperm tail while the 55kDa peptide localizes to the midpiece (By similarity).
CHAIN 1 698 Testis-specific gene 10 protein. /FTId=PRO_0000307125. REGION 556 689 Interaction with HIF1A (By similarity). MOD_RES 163 163 Phosphoserine. MOD_RES 166 166 Phosphothreonine. MOD_RES 171 171 Phosphothreonine. CONFLICT 28 28 T -> EP (in Ref. 2; AAK27309). CONFLICT 273 273 L -> M (in Ref. 5; AAH28366). CONFLICT 365 365 K -> N (in Ref. 2; AAK27309). CONFLICT 624 624 E -> G (in Ref. 2; AAK27309). Back to Top