SpermatogenesisOnline 1.0
 

Tag Content
SG ID
SG00000542 
UniProt Accession
Theoretical PI
9.91  
Molecular Weight
27496 Da  
Genbank Nucleotide ID
Genbank Protein ID
Gene Name
CMTM2 
Gene Synonyms/Alias
CKLFSF2 
Protein Name
CKLF-like MARVEL transmembrane domain-containing protein 2 
Protein Synonyms/Alias
Chemokine-like factor superfamily member 2; 
Organism
Homo sapiens (Human) 
NCBI Taxonomy ID
9606 
Chromosome Location
chr:16;66613351-66622178;1
View in Ensembl genome browser  
Function in Stage
Function in Cell Type
Description
CKLFSF2 could play important roles in the process of meiosis and spermiogenesis, and might be involved in the vesicular transport or membrane apposition events in the endoplasmic reticulum. 
The information of related literatures
1. G. Liu, Z. C. Xin, L. Chen, L. Tian, Y. M. Yuan, W. D. Song, X. J. Jiang and Y. L. Guo (2007) Expression and localization of CKLFSF2 in human spermatogenesis. Asian J Androl 9(2): 189-98. 

Abstract
AIM PMID: [17334588] 

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Figures for illustrating the function of this protein/gene
Ref: G. Liu, Z. C. Xin, L. Chen, L. Tian, Y. M. Yuan, W. D. Song, X. J. Jiang and Y. L. Guo (2007) Expression and localization of CKLFSF2 in human spermatogenesis. Asian J Androl 9(2): 189-98. PMID: [17334588]
Ref: G. Liu, Z. C. Xin, L. Chen, L. Tian, Y. M. Yuan, W. D. Song, X. J. Jiang and Y. L. Guo (2007) Expression and localization of CKLFSF2 in human spermatogenesis. Asian J Androl 9(2): 189-98. PMID: [17334588]
Ref: G. Liu, Z. C. Xin, L. Chen, L. Tian, Y. M. Yuan, W. D. Song, X. J. Jiang and Y. L. Guo (2007) Expression and localization of CKLFSF2 in human spermatogenesis. Asian J Androl 9(2): 189-98. PMID: [17334588]
Function
 
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Subcellular Location
Membrane; Multi-pass membrane protein. 
Tissue Specificity
Highly expressed in testis. 
Gene Ontology
GO IDGO termEvidence
GO:0005615 C:extracellular space IEA:UniProtKB-KW.
GO:0016021 C:integral to membrane IEA:UniProtKB-KW.
GO:0005634 C:nucleus IDA:HPA.
GO:0006935 P:chemotaxis IEA:UniProtKB-KW.
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Interpro
IPR008253;    Marvel.
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Pfam
SMART
PROSITE
PS51225;    MARVEL;    1.
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PRINTS
Created Date
18-Oct-2012 
Record Type
Experiment identified 
Protein sequence Annotation
CHAIN         1    248       CKLF-like MARVEL transmembrane domain-
                             containing protein 2.
                             /FTId=PRO_0000186098.
TRANSMEM    116    136       Helical; (Potential).
TRANSMEM    147    167       Helical; (Potential).
TRANSMEM    178    198       Helical; (Potential).
DOMAIN       82    204       MARVEL.
VARIANT     122    122       I -> T (in dbSNP:rs2290182).
                             /FTId=VAR_022154.
CONFLICT    172    172       R -> Q (in Ref. 2; BAC05345).
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Nucleotide Sequence
Length: 1065 bp   Go to nucleotide: FASTA
Protein Sequence
Length: 248 bp   Go to amino acid: FASTA
The verified Protein-Protein interaction information
UniProt
 Gene Symbol Ref Databases
UBE2AIntAct 
Other Protein-Protein interaction resources
String database  
View Microarray data
Temporarily unavailable 
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