SG ID

SG00000624 

UniProt Accession

TF2LY_HUMAN;Q8IUE0;A2VCU1;  

Theoretical PI

9.84  

Molecular Weight

20814 Da  

Genbank Nucleotide ID

AJ427750; AF332223; AK292609; BC128604;  

Genbank Protein ID

CAD20751.1; AAK13475.1; BAF85298.1; AAI28605.1; 

Gene Name

TGIF2LY 

Gene Synonyms/Alias

TGIFLY 

Protein Name

Homeobox protein TGIF2LY 

Protein Synonyms/Alias

TGF-beta-induced transcription factor 2-like protein; TGFB-induced factor 2-like protein, Y-linked; TGIF-like on the Y; 

Homo sapiens (Human) 

9606 

We found no convincing evidence for association either in allelic or genotypic tests for the total sample or when the sample was stratified by sex. Haplotype T-G-G showed weak association (P = 0.042) with PDAG before correction for multiple testing; association between this haplotype and schizophrenia has been previously reported in an Australian sample. 

The information of related literatures

1.  

Abstract
PMID: [18384078] 

Figures for illustrating the function of this protein/gene

Function

May have a transcription role in testis. May act as acompetitor/regulator of TGIF2LX. 

Subcellular Location

Nucleus (By similarity). 

Tissue Specificity

Specifically expressed in adult testis. 

Gene Ontology

GO ID	GO term	Evidence
GO:0005634	C:nucleus	IEA:UniProtKB-SubCell.
GO:0043565	F:sequence-specific DNA binding	IEA:InterPro.
GO:0003700	F:sequence-specific DNA binding transcription factor activity	IEA:InterPro.
GO:0006351	P:transcription, DNA-dependent	IEA:UniProtKB-KW.

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Interpro

IPR008422;    Homeobox_KN_domain.
IPR001356;    Homeodomain.
IPR009057;    Homeodomain-like.
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Pfam

PF05920;    Homeobox_KN;    1.
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SMART

SM00389;    HOX;    1.
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PROSITE

PS50071;    HOMEOBOX_2;    1.
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PRINTS

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Created Date

18-Oct-2012 

Record Type

Experiment identified 

Protein sequence Annotation

Nucleotide Sequence

Length: 2820 bp   Go to nucleotide: FASTA

Protein Sequence

Length: 185 bp   Go to amino acid: FASTA

The verified Protein-Protein interaction information

UniProt	Gene Symbol	Ref Databases
PHS2_HUMAN	PCBD2	BioGRID

Other Protein-Protein interaction resources

String database  

UniProt	Gene Symbol	Ref Databases
CT47A_HUMAN	CT47A2	String
PABP1_HUMAN	PABPC1	String
PABP2_HUMAN	PABPN1	String
PABP3_HUMAN	PABPC3	String
PABP5_HUMAN	PABPC5	String
PC11Y_HUMAN	PCDH11Y	String
CT47A_HUMAN	CT47A2	String
PABP1_HUMAN	PABPC1	String
PABP2_HUMAN	PABPN1	String
PABP3_HUMAN	PABPC3	String
PABP5_HUMAN	PABPC5	String
PC11Y_HUMAN	PCDH11Y	String
PHS2_HUMAN	PCBD2	String
TGIF2_HUMAN	TGIF2	String
TIA1_HUMAN	TIA1	String
TGIF2_HUMAN	TGIF2	String
TIA1_HUMAN	TIA1	String

View Microarray data

Temporarily unavailable 

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