SG ID

SG00000937 

UniProt Accession

G5E8J4_MOUSE;G5E8J4;  

Theoretical PI

7.25  

Molecular Weight

133531 Da  

Genbank Nucleotide ID

AC124516; AC159193; CH466549; CH466549; CH466549;  

Genbank Protein ID

EDL18927.1; EDL18928.1; EDL18929.1; 

Gene Name

Ptpn21 

Gene Synonyms/Alias

ORFNames=mCG_22432 

Protein Name

 

Protein Synonyms/Alias

SubName: Protein tyrosine phosphatase, non-receptor type 21, isoform CRA_aSubName: Tyrosine-protein phosphatase non-receptor type 21 

Mus musculus (Mouse) 

10090 

PTP-RL10 and its isoform are expressed in the Sertoli cells and are suggested to play roles in spermatogenesis by interacting with c-Src and/or other protein(s). 

The information of related literatures

1. H. Tokuchi, H. Higashitsuji, H. Nishiyama, K. Nonoguchi, T. Nagao, J. H. Xue, K. Itoh, O. Ogawa and J. Fujita (1999) Expression of protein tyrosine phosphatase PTP-RL10 and its isoform in the mouse testis. Int J Urol 6(11): 572-7. 

Abstract
BACKGROUND PMID: [10585123] 

Figures for illustrating the function of this protein/gene

Function

 

Subcellular Location

 

Tissue Specificity

 

Gene Ontology

GO ID	GO term	Evidence
GO:0005856	C:cytoskeleton	IEA:InterPro.
GO:0004725	F:protein tyrosine phosphatase activity	IEA:Compara.

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Interpro

IPR019749;    Band_41_domain.
IPR019750;    Band_41_fam.
IPR014352;    FERM/acyl-CoA-bd_prot_3-hlx.
IPR019748;    FERM_central.
IPR019747;    FERM_CS.
IPR000299;    FERM_domain.
IPR018979;    FERM_N.
IPR018980;    FERM_PH-like_C.
IPR011993;    PH_like_dom.
IPR000387;    Tyr/Dual-specificity_Pase.
IPR016130;    Tyr_Pase_AS.
IPR014392;    Tyr_Pase_non-rcpt_typ-14/21.
IPR000242;    Tyr_Pase_rcpt/non-rcpt.
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Pfam

PF09380;    FERM_C;    1.
PF00373;    FERM_M;    1.
PF09379;    FERM_N;    1.
PF00102;    Y_phosphatase;    1.
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SMART

SM00295;    B41;    1.
SM00194;    PTPc;    1.
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PROSITE

PS00660;    FERM_1;    1.
PS00661;    FERM_2;    1.
PS50057;    FERM_3;    1.
PS00383;    TYR_PHOSPHATASE_1;    1.
PS50056;    TYR_PHOSPHATASE_2;    1.
PS50055;    TYR_PHOSPHATASE_PTP;    1.
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PRINTS

PR00935;    BAND41.;   
PR00700;    PRTYPHPHTASE.;   
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Created Date

18-Oct-2012 

Record Type

Experiment identified 

Protein sequence Annotation

Nucleotide Sequence

Length: 236774 bp   Go to nucleotide: FASTA

Protein Sequence

Length: 1176 bp   Go to amino acid: FASTA

The verified Protein-Protein interaction information

UniProt

Gene Symbol

Ref Databases

Other Protein-Protein interaction resources

String database  

UniProt

Gene Symbol

Ref Databases

View Microarray data

Click to view expression 

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