SG ID

SG00002049 

UniProt Accession

F1LRJ9_RAT;F1LRJ9;  

Theoretical PI

FRAGMENT  

Molecular Weight

52401 Da  

Genbank Nucleotide ID

AC130969;  

Genbank Protein ID

 

Gene Name

Selenbp1 

Gene Synonyms/Alias

 

Protein Name

 

Protein Synonyms/Alias

SubName: Selenium-binding protein 1Flags: Fragment 

Rattus norvegicus (Rat) 

10116 

Temporarily unavailable 

The information of related literatures

1. X. B. He, Y. C. Yan, Y. P. Li and S. S. Koide (2003) Cloning of rat sp56, the homologue of mouse sperm ZP3 receptor-sp56. Cell Res 13(2): 121-9. 

Abstract
Mouse sp56 is considered as one of the candidates for mouse zona pellucida 3 (mZP3) receptor. Up to date, its homologue has only been cloned from guinea pig, namely AM67. Based on the cDNA sequence of mouse sp56, we designed a pair of primer to amplify its homologue from rat testis cDNA. Using RT-PCR, two fragments of 743 bp and 938 bp were amplified. The PCR products show very high homology to mouse sp56. However, the 743 bp product completely lacks one of the seven Sushi domains of mouse sp56. Using the 743 bp product as the probe to detect the expression profile of sp56 in rat tissues, Northern blot shows that a approximately 2.0 kb mRNA expresses specifically in testis. Employed the RACE method, two full cDNA sequences of rat sp56 were obtained. A Mr approximately 42 KD band was detected in denatured and non-reducing protein sample of rat testis and sperm with anti-mouse sp56 monoclonal antibody by Western blot method. Rat sp56 was localized on rat sperm head by the indirect immunofluorescence method. Rat sp56 immunoreactivity was detected from the early pachytene spermatocytes and throughout the spermatogenesis. Its cloning will further our understanding of the mechanism of the sperm-egg recognition and binding. PMID: [12737520] 

Figures for illustrating the function of this protein/gene

Function

 

Subcellular Location

 

Tissue Specificity

 

Gene Ontology

GO ID	GO term	Evidence
GO:0008430	F:selenium binding	IEA:InterPro.

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Interpro

IPR008826;    Se-bd.
IPR015943;    WD40/YVTN_repeat-like_dom.
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Pfam

PF05694;    SBP56;    1.
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SMART

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PROSITE

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PRINTS

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Created Date

18-Oct-2012 

Record Type

Experiment identified 

Protein sequence Annotation

Nucleotide Sequence

Length: 238254 bp   Go to nucleotide: FASTA

Protein Sequence

Length: 471 bp   Go to amino acid: FASTA

The verified Protein-Protein interaction information

UniProt

Gene Symbol

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Other Protein-Protein interaction resources

String database  

UniProt

Gene Symbol

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