SpermatogenesisOnline 1.0

Tag Content
SG ID
SG00004239 
UniProt Accession
Theoretical PI
6.11  
Molecular Weight
14745 Da  
Genbank Nucleotide ID
Genbank Protein ID
Gene Name
Atp5g3 
Gene Synonyms/Alias
 
Protein Name
ATP synthase lipid-binding protein, mitochondrial 
Protein Synonyms/Alias
ATP synthase proteolipid P3; ATPase protein 9; ATPase subunit c;Flags: Precursor 
Organism
Mus musculus (Mouse) 
NCBI Taxonomy ID
10090 
Chromosome Location
chr:2;73746504-73749383;-1
View in Ensembl genome browser  
Function in Stage
Uncertain 
Function in Cell Type
Uncertain 
Probability (GAS) of Function in Spermatogenesis
0.169380686 
The probability was calculated by GAS algorithm, ranging from 0 to 1. The closer it is to 1, the more possibly it functions in spermatogenesis.
Description
Temporarily unavailable 
Abstract of related literatures
1. This study describes comprehensive polling of transcription start and termination sites and analysis of previously unidentified full-length complementary DNAs derived from the mouse genome. We identify the 5' and 3' boundaries of 181,047 transcripts with extensive variation in transcripts arising from alternative promoter usage, splicing, and polyadenylation. There are 16,247 new mouse protein-coding transcripts, including 5154 encoding previously unidentified proteins. Genomic mapping of the transcriptome reveals transcriptional forests, with overlapping transcription on both strands, separated by deserts in which few transcripts are observed. The data provide a comprehensive platform for the comparative analysis of mammalian transcriptional regulation in differentiation and development. PMID: [16141072] 

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Function
Mitochondrial membrane ATP synthase (F(1)F(0) ATPsynthase or Complex V) produces ATP from ADP in the presence of aproton gradient across the membrane which is generated by electrontransport complexes of the respiratory chain. F-type ATPasesconsist of two structural domains, F(1) - containing theextramembraneous catalytic core and F(0) - containing the membraneproton channel, linked together by a central stalk and aperipheral stalk. During catalysis, ATP synthesis in the catalyticdomain of F(1) is coupled via a rotary mechanism of the centralstalk subunits to proton translocation. Part of the complex F(0)domain. A homomeric c-ring of probably 10 subunits is part of thecomplex rotary element. 
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Subcellular Location
Mitochondrion membrane; Multi-pass membraneprotein (By similarity). 
Tissue Specificity
 
Gene Ontology
GO IDGO termEvidence
GO:0016021 C:integral to membrane IEA:UniProtKB-KW.
GO:0031966 C:mitochondrial membrane IEA:UniProtKB-SubCell.
GO:0005739 C:mitochondrion IDA:MGI.
GO:0045263 C:proton-transporting ATP synthase complex, coupling factor F(o) IEA:UniProtKB-KW.
GO:0015078 F:hydrogen ion transmembrane transporter activity IEA:InterPro.
GO:0008289 F:lipid binding IEA:UniProtKB-KW.
GO:0007568 P:aging IEA:Compara.
GO:0015991 P:ATP hydrolysis coupled proton transport IEA:InterPro.
GO:0015986 P:ATP synthesis coupled proton transport IEA:InterPro.
GO:0045471 P:response to ethanol IEA:Compara.
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Interpro
IPR000454;    ATPase_F0-cplx_csu.
IPR020537;    ATPase_F0-cplx_csu_DDCD_BS.
IPR002379;    ATPase_F0/V0-cplx_csu.
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Pfam
PF00137;    ATP-synt_C;    1.
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SMART
PROSITE
PS00605;    ATPASE_C;    1.
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PRINTS
PR00124;    ATPASEC.;   
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Created Date
18-Oct-2012 
Record Type
GAS predicted 
Sequence Annotation
TRANSIT       1     66       Mitochondrion (By similarity).
CHAIN        67    141       ATP synthase lipid-binding protein,
                             mitochondrial.
                             /FTId=PRO_0000002568.
TRANSMEM     82    102       Helical; (Potential).
TRANSMEM    117    137       Helical; (Potential).
SITE        124    124       Reversibly protonated during proton
                             transport (By similarity).
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Nucleotide Sequence
Length: 681 bp   Go to nucleotide: FASTA
Protein Sequence
Length: 141 bp   Go to amino acid: FASTA
The verified Protein-Protein interaction information
UniProt
 Gene Symbol Ref Databases
Other Protein-Protein interaction resources
String database  
View Microarray data
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