Tag Content
UniProt Accession
Theoretical PI
Molecular Weight
46572 Da  
Genbank Nucleotide ID
Genbank Protein ID
Gene Name
Gene Synonyms/Alias
Protein Name
Phosphorylase b kinase gamma catalytic chain, testis/liver isoform 
Protein Synonyms/Alias
PHK-gamma-TEC= Phosphorylase kinase subunit gamma-2; Serine/threonine-protein kinase PHKG2;EC= 
Mus musculus (Mouse) 
NCBI Taxonomy ID
Chromosome Location
View in Ensembl genome browser  
Function in Stage
Function in Cell Type
Probability (GAS) of Function in Spermatogenesis
The probability was calculated by GAS algorithm, ranging from 0 to 1. The closer it is to 1, the more possibly it functions in spermatogenesis.
Temporarily unavailable 
Abstract of related literatures
1. This study describes comprehensive polling of transcription start and termination sites and analysis of previously unidentified full-length complementary DNAs derived from the mouse genome. We identify the 5' and 3' boundaries of 181,047 transcripts with extensive variation in transcripts arising from alternative promoter usage, splicing, and polyadenylation. There are 16,247 new mouse protein-coding transcripts, including 5154 encoding previously unidentified proteins. Genomic mapping of the transcriptome reveals transcriptional forests, with overlapping transcription on both strands, separated by deserts in which few transcripts are observed. The data provide a comprehensive platform for the comparative analysis of mammalian transcriptional regulation in differentiation and development. PMID: [16141072] 

2. The National Institutes of Health's Mammalian Gene Collection (MGC) project was designed to generate and sequence a publicly accessible cDNA resource containing a complete open reading frame (ORF) for every human and mouse gene. The project initially used a random strategy to select clones from a large number of cDNA libraries from diverse tissues. Candidate clones were chosen based on 5'-EST sequences, and then fully sequenced to high accuracy and analyzed by algorithms developed for this project. Currently, more than 11,000 human and 10,000 mouse genes are represented in MGC by at least one clone with a full ORF. The random selection approach is now reaching a saturation point, and a transition to protocols targeted at the missing transcripts is now required to complete the mouse and human collections. Comparison of the sequence of the MGC clones to reference genome sequences reveals that most cDNA clones are of very high sequence quality, although it is likely that some cDNAs may carry missense variants as a consequence of experimental artifact, such as PCR, cloning, or reverse transcriptase errors. Recently, a rat cDNA component was added to the project, and ongoing frog (Xenopus) and zebrafish (Danio) cDNA projects were expanded to take advantage of the high-throughput MGC pipeline. PMID: [15489334] 

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Catalytic subunit of the phosphorylase b kinase (PHK),which mediates the neural and hormonal regulation of glycogenbreakdown (glycogenolysis) by phosphorylating and therebyactivating glycogen phosphorylase (PYGB, PYGL or PYGM). Mayregulate glycogeneolysis in the testis. In vitro, phosphorylatesTNNI3, TNNT2, MAPT/TAU, GAP43 and NRGN/RC3 (By similarity). 
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Subcellular Location
Tissue Specificity
Gene Ontology
GO IDGO termEvidence
GO:0005964 C:phosphorylase kinase complex IEA:Compara.
GO:0005625 C:soluble fraction IEA:Compara.
GO:0005524 F:ATP binding IEA:UniProtKB-KW.
GO:0004689 F:phosphorylase kinase activity IEA:EC.
GO:0050321 F:tau-protein kinase activity IEA:EC.
GO:0005978 P:glycogen biosynthetic process IEA:InterPro.
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IPR011009;    Kinase-like_dom.
IPR002291;    Phosph_kin_gamma.
IPR000719;    Prot_kinase_cat_dom.
IPR017441;    Protein_kinase_ATP_BS.
IPR002290;    Ser/Thr_dual-sp_kinase_dom.
IPR008271;    Ser/Thr_kinase_AS.
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PF00069;    Pkinase;    1.
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SM00220;    S_TKc;    1.
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PS00107;    PROTEIN_KINASE_ATP;    1.
PS50011;    PROTEIN_KINASE_DOM;    1.
PS00108;    PROTEIN_KINASE_ST;    1.
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PR01049;    PHOSPHBKNASE.;   
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Created Date
Record Type
GAS predicted 
Sequence Annotation
CHAIN         1    406       Phosphorylase b kinase gamma catalytic
                             chain, testis/liver isoform.
DOMAIN       24    291       Protein kinase.
NP_BIND      30     38       ATP (By similarity).
REGION      306    330       Calmodulin-binding (domain-N) (By
REGION      346    370       Calmodulin-binding (domain-C) (By
ACT_SITE    153    153       Proton acceptor (By similarity).
BINDING      53     53       ATP (By similarity).
CONFLICT    260    260       R -> C (in Ref. 1; BAB23926).
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Nucleotide Sequence
Length: 1567 bp   Go to nucleotide: FASTA
Protein Sequence
Length: 406 bp   Go to amino acid: FASTA
The verified Protein-Protein interaction information
Gene Symbol Ref Databases
Other Protein-Protein interaction resources
String database  
View Microarray data