Tag Content
SG ID
SG00012758 
UniProt Accession
Theoretical PI
6.9  
Molecular Weight
12747 Da  
Genbank Nucleotide ID
Genbank Protein ID
Gene Name
Eif1 
Gene Synonyms/Alias
Sui1, Sui1-rs1 
Protein Name
Eukaryotic translation initiation factor 1 
Protein Synonyms/Alias
eIF1 Protein translation factor SUI1 homolog; 
Organism
Mus musculus (Mouse) 
NCBI Taxonomy ID
10090 
Chromosome Location
chr:11;100181199-100183410;1
View in Ensembl genome browser  
Function in Stage
Uncertain 
Function in Cell Type
Uncertain 
Probability (GAS) of Function in Spermatogenesis
0.918466861 
The probability was calculated by GAS algorithm, ranging from 0 to 1. The closer it is to 1, the more possibly it functions in spermatogenesis.
Description
Temporarily unavailable 
Abstract of related literatures
1. The National Institutes of Health's Mammalian Gene Collection (MGC) project was designed to generate and sequence a publicly accessible cDNA resource containing a complete open reading frame (ORF) for every human and mouse gene. The project initially used a random strategy to select clones from a large number of cDNA libraries from diverse tissues. Candidate clones were chosen based on 5'-EST sequences, and then fully sequenced to high accuracy and analyzed by algorithms developed for this project. Currently, more than 11,000 human and 10,000 mouse genes are represented in MGC by at least one clone with a full ORF. The random selection approach is now reaching a saturation point, and a transition to protocols targeted at the missing transcripts is now required to complete the mouse and human collections. Comparison of the sequence of the MGC clones to reference genome sequences reveals that most cDNA clones are of very high sequence quality, although it is likely that some cDNAs may carry missense variants as a consequence of experimental artifact, such as PCR, cloning, or reverse transcriptase errors. Recently, a rat cDNA component was added to the project, and ongoing frog (Xenopus) and zebrafish (Danio) cDNA projects were expanded to take advantage of the high-throughput MGC pipeline. PMID: [15489334] 


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Function
Necessary for scanning and involved in initiation siteselection. Promotes the assembly of 48S ribosomal complexes at theauthentic initiation codon of a conventional capped mRNA (Bysimilarity). 
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Subcellular Location
 
Tissue Specificity
 
Gene Ontology
GO IDGO termEvidence
GO:0003743 F:translation initiation factor activity IEA:UniProtKB-KW.
GO:0009048 P:dosage compensation by inactivation of X chromosome IMP:MGI.
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Interpro
IPR005874;    SUI1_euk.
IPR001950;    TIF_SUI1.
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Pfam
PF01253;    SUI1;    1.
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SMART
PROSITE
PS50296;    SUI1;    1.
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PRINTS
Created Date
18-Oct-2012 
Record Type
GAS predicted 
Sequence Annotation
CHAIN         1    113       Eukaryotic translation initiation factor
                             1.
                             /FTId=PRO_0000130555.
MOD_RES       1      1       N-acetylmethionine (By similarity).
MOD_RES      30     30       Phosphotyrosine (By similarity).
MOD_RES      58     58       N6-acetyllysine (By similarity).
MOD_RES      61     61       N6-acetyllysine (By similarity).
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Nucleotide Sequence
Length: 1250 bp   Go to nucleotide: FASTA
Protein Sequence
Length: 113 bp   Go to amino acid: FASTA
The verified Protein-Protein interaction information
UniProt
Gene Symbol Ref Databases
Other Protein-Protein interaction resources
String database  
View Microarray data
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