Tag Content
SG ID
SG00019890 
UniProt Accession
Theoretical PI
10.39  
Molecular Weight
17040 Da  
Genbank Nucleotide ID
Genbank Protein ID
Gene Name
Rps15 
Gene Synonyms/Alias
Rig 
Protein Name
40S ribosomal protein S15 
Protein Synonyms/Alias
RIG protein; 
Organism
Mus musculus (Mouse) 
NCBI Taxonomy ID
10090 
Chromosome Location
chr:10;79755176-79756859;1
View in Ensembl genome browser  
Function in Stage
Uncertain 
Function in Cell Type
Uncertain 
Probability (GAS) of Function in Spermatogenesis
0.019538955 
The probability was calculated by GAS algorithm, ranging from 0 to 1. The closer it is to 1, the more possibly it functions in spermatogenesis.
Description
Temporarily unavailable 
Abstract of related literatures
1. Mouse, chicken and Xenopus laevis homologues to rig (rat insulinoma gene) cDNA were isolated and their nucleotide sequences were determined. Each homologue encoded a 145-amino acid protein; the amino acid sequence remained invariant in the murine and avian genes, and there were only 6 amino acid substitutions in the salientian gene. The evolutionary rate calculated for rig mRNA was sufficiently low to be viewed as evidence that rig is vital to vertebrate species. Southern blot analysis indicated that haploid sets of the mammalian genomes contain several copies of rig or rig-related sequences, whereas there appeared to be only one copy in the amphibian and bird genomes. The possibility that rig belongs to the class of housekeeping genes is discussed. PMID: [2154983] 

2. The National Institutes of Health's Mammalian Gene Collection (MGC) project was designed to generate and sequence a publicly accessible cDNA resource containing a complete open reading frame (ORF) for every human and mouse gene. The project initially used a random strategy to select clones from a large number of cDNA libraries from diverse tissues. Candidate clones were chosen based on 5'-EST sequences, and then fully sequenced to high accuracy and analyzed by algorithms developed for this project. Currently, more than 11,000 human and 10,000 mouse genes are represented in MGC by at least one clone with a full ORF. The random selection approach is now reaching a saturation point, and a transition to protocols targeted at the missing transcripts is now required to complete the mouse and human collections. Comparison of the sequence of the MGC clones to reference genome sequences reveals that most cDNA clones are of very high sequence quality, although it is likely that some cDNAs may carry missense variants as a consequence of experimental artifact, such as PCR, cloning, or reverse transcriptase errors. Recently, a rat cDNA component was added to the project, and ongoing frog (Xenopus) and zebrafish (Danio) cDNA projects were expanded to take advantage of the high-throughput MGC pipeline. PMID: [15489334] 

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Function
 
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Subcellular Location
 
Tissue Specificity
 
Gene Ontology
GO IDGO termEvidence
GO:0022627 C:cytosolic small ribosomal subunit IEA:Compara.
GO:0003723 F:RNA binding IEA:InterPro.
GO:0003735 F:structural constituent of ribosome IEA:InterPro.
GO:0042274 P:ribosomal small subunit biogenesis IEA:Compara.
GO:0000056 P:ribosomal small subunit export from nucleus IEA:Compara.
GO:0006364 P:rRNA processing IEA:Compara.
GO:0006412 P:translation IEA:InterPro.
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Interpro
IPR002222;    Ribosomal_S19.
IPR020934;    Ribosomal_S19_CS.
IPR023575;    Ribosomal_S19_SF.
IPR005713;    Ribosomal_S19A/S15e.
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Pfam
PF00203;    Ribosomal_S19;    1.
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SMART
PROSITE
PS00323;    RIBOSOMAL_S19;    1.
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PRINTS
PR00975;    RIBOSOMALS19.;   
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Created Date
18-Oct-2012 
Record Type
GAS predicted 
Sequence Annotation
INIT_MET      1      1       Removed (By similarity).
CHAIN         2    145       40S ribosomal protein S15.
                             /FTId=PRO_0000130029.
MOD_RES       2      2       N-acetylalanine (By similarity).
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Nucleotide Sequence
Length: 500 bp   Go to nucleotide: FASTA
Protein Sequence
Length: 145 bp   Go to amino acid: FASTA
The verified Protein-Protein interaction information
UniProt
Gene Symbol Ref Databases
EedIntAct 
Npm1MINT 
Other Protein-Protein interaction resources
String database  
View Microarray data
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