SpermatogenesisOnline 1.0

Tag Content
SG ID
SG00022645 
UniProt Accession
Theoretical PI
10.53  
Molecular Weight
17222 Da  
Genbank Nucleotide ID
Genbank Protein ID
Gene Name
Rps13 
Gene Synonyms/Alias
 
Protein Name
40S ribosomal protein S13 
Protein Synonyms/Alias
 
Organism
Mus musculus (Mouse) 
NCBI Taxonomy ID
10090 
Chromosome Location
chr:7;123475021-123477704;-1
View in Ensembl genome browser  
Function in Stage
Uncertain 
Function in Cell Type
Uncertain 
Probability (GAS) of Function in Spermatogenesis
0.638976087 
The probability was calculated by GAS algorithm, ranging from 0 to 1. The closer it is to 1, the more possibly it functions in spermatogenesis.
Description
Temporarily unavailable 
Abstract of related literatures
1. This study describes comprehensive polling of transcription start and termination sites and analysis of previously unidentified full-length complementary DNAs derived from the mouse genome. We identify the 5' and 3' boundaries of 181,047 transcripts with extensive variation in transcripts arising from alternative promoter usage, splicing, and polyadenylation. There are 16,247 new mouse protein-coding transcripts, including 5154 encoding previously unidentified proteins. Genomic mapping of the transcriptome reveals transcriptional forests, with overlapping transcription on both strands, separated by deserts in which few transcripts are observed. The data provide a comprehensive platform for the comparative analysis of mammalian transcriptional regulation in differentiation and development. PMID: [16141072] 

2. Metazoans employ reversible tyrosine phosphorylation to regulate innumerable biological processes. Thus, the large-scale identification of tyrosine phosphorylation sites from primary tissues is an essential step toward a molecular systems understanding of dynamic regulation in vivo. The relative paucity of phosphotyrosine has greatly limited its identification in large-scale phosphoproteomic experiments. However, using antiphosphotyrosine peptide immunoprecipitations, we report the largest study to date of tyrosine phosphorylation sites from primary tissue, identifying 414 unique tyrosine phosphorylation sites from murine brain. To measure the conservation of phosphorylated tyrosines and their surrounding residues, we constructed a computational pipeline and identified patterns of conservation within the signature of phosphotyrosine. PMID: [18034455] 

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Function
 
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Subcellular Location
 
Tissue Specificity
 
Gene Ontology
GO IDGO termEvidence
GO:0022627 C:cytosolic small ribosomal subunit IEA:Compara.
GO:0005730 C:nucleolus IEA:Compara.
GO:0003729 F:mRNA binding IEA:Compara.
GO:0003735 F:structural constituent of ribosome IEA:InterPro.
GO:0033119 P:negative regulation of RNA splicing IEA:Compara.
GO:0006412 P:translation IEA:InterPro.
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Interpro
IPR012606;    Ribosomal_S13/S15_N.
IPR000589;    Ribosomal_S15.
IPR023029;    Ribosomal_S15P.
IPR009068;    S15_NS1_RNA-bd.
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Pfam
PF08069;    Ribosomal_S13_N;    1.
PF00312;    Ribosomal_S15;    1.
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SMART
PROSITE
PS00362;    RIBOSOMAL_S15;    1.
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PRINTS
Created Date
18-Oct-2012 
Record Type
GAS predicted 
Sequence Annotation
INIT_MET      1      1       Removed (By similarity).
CHAIN         2    151       40S ribosomal protein S13.
                             /FTId=PRO_0000115662.
MOD_RES      12     12       Phosphoserine (By similarity).
MOD_RES      27     27       N6-acetyllysine (By similarity).
MOD_RES      30     30       Phosphoserine (By similarity).
MOD_RES      38     38       Phosphotyrosine.
MOD_RES      39     39       N6-acetyllysine (By similarity).
MOD_RES     128    128       Phosphotyrosine (By similarity).
MOD_RES     129    129       Phosphotyrosine (By similarity).
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Nucleotide Sequence
Length: 522 bp   Go to nucleotide: FASTA
Protein Sequence
Length: 151 bp   Go to amino acid: FASTA
The verified Protein-Protein interaction information
UniProt
 Gene Symbol Ref Databases
Other Protein-Protein interaction resources
String database  
View Microarray data
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