FertilityOnline | Spermatogenes

Detail Information of SG013155

SG ID

SG013155

Gene Name

APOA2

Gene Synonyms/Alias

Apo-AII, ApoA-II, apoAII

Organism

Homo sapiens

NCBI Taxonomy ID

9606

Ensembl Gene ID

Ensembl Protein ID

Description

apolipoprotein A2 [Homo sapiens (human)]

Orthology

Status

Nonfunctional gene(KO mice without reproductive phenotype)

Function in Stage
Function in Cell Type
The information of related literature
Figures for illustrating the function of this protein/gene
Functional description	-
Protein complex
Pathway	ReactomeID: R-HSA-975634 Retinoid metabolism and transport
Human diseases	Hypercholesterolemia familial
OMIM	107670
Spermatogenesis failure

Tissue specificity (in Homo sapiens)	Expressed highest in liver
Testicular Cell specificity (in Mus musculus)	Expressed highest in sertoli cell
Testicular scRNA-seq (in Homo sapiens)	View detail
Testicular scRNA-seq (in Mus musculus)	View detail
Subcellular location	Secreted

Variants founded in public databases	1000G (Phase 3): 23 ESP6500 (SI-V2): 22 ExAC (r0.3.1): 168 dbSNP(Build 147): 238
Variants founded in in-house datasets	Chinese health control (254): 1 European health control (283): Chinese patients (168):
De novo Mutation Rate	Gene Name: APOA2 DNMR-average: 0.00000447175 DNMR-SC: 0.00000418348

Protein-Protein interaction information

Protein family and Domain