| Complex name | Subunits(UniProt IDs) | Functional comment |
| ITGA5-ITGB1-FN1-TGM2 complex | P02751 P08648 P05556
P21980 | The tissue transglutaminase mediates the interaction of integrins with fibronectin, thereby acting as an integrin-associated coreceptor to promote cell adhesion and spreading. |
| ITGA5-ITGB1-ADAM15 complex | Q13444 P08648 P05556 | |
| ITGA5-ITGB4 complex | P08648 P05556 | |
| Itga5-Itgb1-Fn1-Sfrp2 complex | Q28275 P08648 P05556
Q863H1 | |
| ITGA5-ITGB1-FN-1-NOV complex | P02751 P08648 P05556
P48745 | The involvement of alpha5-beta1 in the process of endothelial cell adhesion to NOV was mediated by fibronectin. |
| ITGA5-ITGB1-CAL4A3 complex | P39060 P08648 P05556 | Endostatin binding to alpha5-beta1 integrin leads to the inhibition of focal adhesion kinase/c-Raf/MEK1/2/p38/ERK1 mitogen-activated protein kinase pathway, with no effect on phosphatidylinositol 3-kinase/Akt/mTOR/4E-BP1 and Cap-dependent translation. |
| ITGA5-ITGB3-COL6A3 complex | P12111 P08648 P05106 | |
| ITGA5-ITGB1-SPP1 complex | P08648 P05556 P10451 | |