FertilityOnline | Spermatogenes

Detail Information of SG029121

SG ID

SG029121

Gene Name

Ly86

Gene Synonyms/Alias

MD-1, MD1, ly86_tv2

Organism

Mus musculus

NCBI Taxonomy ID

10090

Ensembl Gene ID

Ensembl Protein ID

Description

lymphocyte antigen 86 [Mus musculus (house mouse)]

Orthology

Status

Nonfunctional gene(KO mice without reproductive phenotype)

Function in Stage
Function in Cell Type
The information of related literature
Figures for illustrating the function of this protein/gene
Functional description	-
Protein complex
Pathway	ReactomeID: R-MMU-166016 Toll Like Receptor 4 (TLR4) Cascade
Human diseases
OMIM
Spermatogenesis failure

Tissue specificity (in Homo sapiens)	Expressed highest in lymph node
Testicular Cell specificity (in Mus musculus)	Expressed highest in sperm
Testicular scRNA-seq (in Homo sapiens)	View detail
Testicular scRNA-seq (in Mus musculus)	View detail
Subcellular location	Secreted, extracellular space.

Variants founded in public databases

1000G (Phase 3): 952 ESP6500 (SI-V2): 49 ExAC (r0.3.1): 231 dbSNP(Build 147): 2025

Variants founded in in-house datasets

Chinese health control (254): 2 European health control (283): Chinese patients (168):

De novo Mutation Rate

Gene Name	DNMR-average	DNMR-SC
LY86	0.000006753	0.0000066256

Protein-Protein interaction information

Protein family and Domain