FertilityOnline | Spermatogenes

Detail Information of SG048870

General information

SG ID	SG048870
Gene Name	DDX52
Gene Synonyms/Alias
Organism	Eriocheir sinensis
NCBI Taxonomy ID	95602
Ensembl Gene ID
Ensembl Protein ID
Description
Orthology
Status	Reviewed functional gene

Functional information

Function in Stage	postmeiotic meiotic premeiotic
Function in Cell Type	Spermatocyte Spermatid Sertoli cell
The information of related literature
Figures for illustrating the function of this protein/gene	PMID: [29288727] PMID: [29288727] PMID: [29288727] PMID: [29288727] PMID: [29288727] PMID: [29288727] PMID: [29288727] PMID: [29288727] PMID: [29288727] PMID: [29288727]
Functional description	DDX52 (DExD-Box Helicase 52) is a Protein Coding gene.DDX52 functions in cell devision and spermatogensis and it may participate in regulation of P-bodies and microtubules by Es-XRN1, and involved in the mitosis of spermatonia and spermatid differentiation.
Protein complex
Pathway
Human diseases
OMIM
Spermatogenesis failure

Expression and location

Tissue specificity (in Homo sapiens)	Expressed highest in cerebral cortex
Testicular Cell specificity (in Mus musculus)	Expressed highest in spermatocyte
Testicular scRNA-seq (in Homo sapiens)	View detail
Testicular scRNA-seq (in Mus musculus)	View detail
Subcellular location

Mutation in human orthology

Variants founded in public databases	1000G (Phase 3): ESP6500 (SI-V2): ExAC (r0.3.1): dbSNP(Build 147):
Variants founded in in-house datasets	Chinese health control (254): European health control (283): Chinese patients (168):
De novo Mutation Rate

Other information

GO

Protein-Protein interaction information

Protein A	Gene name A	Protein B	Gene name B	Evidence
ENSMUSP00000048802	Ddx52	ENSMUSP00000048833	Eif4h	experimental
ENSMUSP00000048802	Ddx52	ENSMUSP00000049705		predicted
ENSMUSP00000048802	Ddx52	ENSMUSP00000049973	Haus3	predicted

Protein family and Domain