Molecular&Cell Genetics Laboratory
Mol&Cell Genet
English Version
主要论文(*:corresponding author;IF=2015年影响因子;NC=至17年5月被引用次数)
1. Shi Q, King RW. Chromosome nondisjunction yields tetraploid rather than aneuploid cells in human cell lines. Nature 437:1038-1042, 2005 (IF=38.183; NC=336).
2. Pan H, Zhang X, Jiang H, Jiang X, Wang L, Qi Q, Bi Y, Wang J, Shi Q*, and Li R*. Ndrg3 gene regulates DSB repair during meiosis through modulation the ERK signal pathway in the male germ cells. Sci. Rep. 7:44440, 2017 (IF=5.228)

3. Zhang T, Lv L, Huang Y, Ren X, and Shi Q*. Chromosome nondisjunction during bipolar mitoses of binucleated intermediates promote aneuploidy formation along with multipolar mitoses rather than chromosome loss in micronuclei induced by asbestos.  Oncotarget. 8(7):11030-11041, 2017 (IF=5.008)

4. Liu C, Li M, Li T, Zhao H, Huang J, Wang Y, Gao Q, Yu Y*, and Shi Q*. ECAT1 is essential for human oocyte maturation and pre-implantation development of the resulting embryos. Sci. Rep. 7:44440, 2017 (IF=5.228)

5.Zhang Y, Zang Q, Zhang H, Ban R, Yang Y, Iqbal F, Li A, and Shi Q*. DeAnnCNV: a tool for online detection and annotation of copy number variations from whole-exome sequencing data Nucleic Acids Res 44(W1):W166-175, 2016. (IF=9.202;NC=4)

6.Zhang Y, Zang Q, Xu B, Zheng W, Ban R, Zhang H, Yang Y, Hao Q, Iqbal F, Li A and Shi Q*. IsomiR Bank: a research resource for tracking IsomiRs. Bioinformatics 32(13):2069-71. 2016. (IF=5.776; NC=5)

7.Zhou Q, Wang M, Yuan Y, Wang X, Fu R, Wan H, Xie M, Liu M, Guo X, Zheng Y, Feng G, Shi Q, Zhao XY, Sha J, Zhou Q. Complete Meiosis from Embryonic Stem Cell-Derived Germ Cells In?Vitro.  Cell Stem Cell 18(3):330-340. 2016. (IF=22.387; NC=49)

8. Wu C, Wang L, Iqbal F, Jiang X, Bukhari I, Guo T, Yin G, Cooke HJ, Cao Z, Jiang H and Shi Q* Preferential Y-Y pairing and synapsis and abnormal meiotic recombination in a 47,XYY man with non obstructive azoospermia.  Mol Cytogenet. 9:9. 2016. (IF=1.506; NC=1)

9. Sun R, Sun YC, Ge W, Tan H, Cheng SF, Yin S, Sun XF, Li L, Dyce P, Li J, Yang X and Shi QH* The crucial role of Activin A on the formation of primordial germ cell-like cells from skin-derived stem cells in vitro.  Cell Cycle. 14(19):3016-29 2015. (IF=3.952; NC=4)

10. Ge W, Ma HG, Cheng SF, Sun YC, Sun LL, Sun XF, Li L, Dyce P, Li J, Shi QH* and Shen W. Differentiation of early germ cells from human skin-derived stem cells without exogenous gene integration.  Sci Rep. 5:13822, 2015. (IF=5.228; NC=8)

11. Zhang Y, Yu Z, Ban R, Zhang H, Iqbal F, Zhao A, Li A and Shi Q*. DeAnnCNV: a tool for online detection and annotation of copy number variations from whole-exome sequencing data.  Nucleic Acids Res. 43(W1):W289-94 2015. (IF=9.202; NC=1)

12.Chu B, Zhong L, Dou S, Wang J, Li J, Wang M,, Shi Q* , Mei Y, Wu M. miRNA-181 regulates embryo implantation in mice through targeting leukemia inhibitory factor. Mol Cell Biol 7(1):12-22,2015. (IF=6.459; NC=18)

13.Wang L, Xu Z, Iqbal F, Zhong L, Zhang Y, Wu C, Zhou G, Jiang H, Bukhari I, Cooke HJ, Shi Q*. Decreased XY recombination and disturbed meiotic prophase I progression in an infertile 48, XYY, +sSMC man Chromosome Res 23(2):267-76,2015 (IF=2.59; NC=1)

14. Jiang X, Ma T, Zhang Y, Zhang H, Yin S, Zheng W, Wang L, Wang Z, Khan M, Sheikh SW, Bukhari I, Iqbal F, Cooke HJ, Shi Q*. Specific Deletion of Cdh2 in Sertoli Cells Leads to Altered Meiotic Progression and Subfertility of Mice Biology of Reproduction 92(3):1-12,2015 (IF=3.471; NC=6)

15. Hua J, Xu B, Yang Y, Ban R, Iqbal F, Cooke HJ, Zhang Y, Shi Q*. Follicle Online: an integrated database of follicle assembly, development and ovulation. Database (Oxford). 2015 Apr 29; 2015:bav036.(IF=3.372; NC=4)
16. Wang L, Iqbal F, Li G, Jiang X, Bukhari I, Jiang H, Yang Q, Zhong L, Zhang Y, Hua J, Cooke HJ, Shi Q*. Abnormal meiotic recombination with complex chromosomal rearrangement in an azoospermic man. Reprod Biomed Online. 30(6):651-8,2015.(IF=2.796; NC=4)
17. Gao X, Ma W, Nie J, Zhang C, Zhang J, Yao G, Han J, Xu J, Hu B, Du Y, Shi Q,Yang Z, Huang X,Zhang Y. A G-quadruplex DNA structure resolvase, RHAU, is essential for spermatogonia differentiation. Cell Death Dis 2015 Jan 22;6:e1610.(IF=5.378; NC=9)
18. Zheng Wang, Hao Yin, Yuanwei Zhang, Yukun Feng, Zhaofeng Yan, Xiaohua Jiang, Ihtisham Bukhari, Furhan Iqbal, Howard J Cooke, and Qinghua Shi*. miR-214-mediated downregulation of RNF8 induces chromosomal instability in ovarian cancer cells Cell Cycle 13(2):3519-3528,2014.(IF=3.952; NC=8)
19. Xiaohua Jiang, Huan Zhang, Shi Yin, Yuanwei Zhang, Weimei Yang, Wei Zheng, Liu Wang,Zheng Wang, Ihtisham Bukhari, Howard J. Cooke1, Furhan Iqbal & Qinghua Shi*. Specific deficiency of Plzf paralog, Zbtb20, in Sertoli cells does not affect spermatogenesis and fertility in mice Sci Rep 4:7062,2014.(IF=5.228; NC=4)
20. Ma H, Cooke HJ, Shi Q*. Meiosis: Recent Progress and New Opportunities Journal of Genetics and Genomics 41(3):83-5,2014.(IF=3.981; NC=2)
21. Hanwei Jiang , Liu Wang , Yingxia Cui , Zhipeng Xu , Tonghang Guo, Dongkai Cheng,Peng Xu, Wen Yu, Qinghua Shi*. Meiotic Chromosome Behavior in a Human Male t(8;15) Carrier Journal of Genetics and Genomics 41(3):177-85,2014.(IF=3.981; NC=10)
22. Yao Q, Wang L, Yao B, Gao H, Li W, Xia X, Shi Q,Cui Y. Meiotic prophase I defects in an oligospermic man with Wolf-Hirschhorn syndrome with ring chromosome 4. Mol Cytogenet. 2014, 7:45. doi: 10.1186/1755-8166-7-45.(IF=1.506; NC=2)
23.Wang J, Qian J, Hu Y, Kong X, Chen H, Shi Q,Jiang L, Wu C, Zou W, Chen Y, Xu J, Fang JY. ArhGAP30 promotes p53 acetylation and function in colorectal cancer. Nat Commun. 2014, 5:4735.(IF=11.329;NC=12)
24. Jiang XH, Bukhari I, Zheng W, Yin S, Wang Z, Cooke HJ, Shi QH* . Blood-testis barrier and spermatogenesis: lessons from genetically-modified mice Asian J Androl 16(4):572-80,2014(IF=2.644;NC=24)
25.Huan Zhang, Xiaohua Jiang, Yuanwei Zhang, Bo Xu, Juan Hua, Tieliang Ma,Wei Zheng,Rui Sun, Wei Shen, Howard J Cooke, Qiaomei Hao, Jie Qiao and Qinghua Shi*. microRNA 376a regulates follicle assembly by targeting Pcna in fetal and neonatal mouse ovaries hybrid cells Reproduction 148(1):43-54,2014(IF=3.184;NC=25)
26.Zheng Wang, Hao Yin, Lei Lv, Yingying Feng, Shaopeng Chen, Junting Liang, Yun Huang, Xiaohua Jiang, Hanwei Jiang,Ihtisham Bukhari, Lijun Wu, Howard J Cooke, and Qinghua Shi*. Unrepaired DNA damage facilitates elimination of uniparental chromosomes in interspecific hybrid cells Cell Cycle 13(8):1345-56,2014 (IF=3.952;NC=8)
27. Yang Q,Hua J,Wang L,Xu B,Zhang H,Ye N,Zhang Z,Yu D,Cooke HJ,Zhang Y,Shi Q *. MicroRNA and piRNA Profiles in Normal Human Testis Detected by Next Generation Sequencing Plos one 8(6):e66809, 2013 (IF=3.057;NC=52)
28.Wu J,Liu Q,Wang X,Zheng J,Sheng Sun Z, Shi Q*. mirTools 2.0 for non-coding RNA discovery, profiling and functional annotation based on high-throughput sequencing RNA Biol 10(7), 2013 (IF=4.076;NC=33)
29. Zhang Y, Zhong L, Xu B, Yang Y, Ban R, Zhu J, Cooke HJ, Hao Q, Shi Q*. SpermatogenesisOnline 1.0: a resource for spermatogenesis based on manual literature curation and genome-wide data mining. Nucleic Acids Res 41:D1055-62,2013 (IF=9.202; NC=9)
30. Wang XX, Ying P, Diao F, Wang Q, Ye D, Jiang C, Shen N, Xu N, Chen WB, Lai SS, Jiang S, Miao XL, Feng J, Tao WW, Zhao NW, Yao B, Xu ZP, Sun HX, Li JM, Sha JH, Huang XX, Shi Q,Tang H, Gao X,Li CJ. Altered protein prenylation in Sertoli cells is associated with adult infertility resulting from childhood mumps infection. J Exp Med. 2013, 210(8):1559-74.(IF=11.24; NC=16)
31. Lv L,Zhang T,Yi Q,Huang Y,Wang Z,Hou H,Zhang H,Zhang W,Hao Q,Guo Z,Cooke HJ, Shi Q*. Tetraploid cells from cytokinesis failure induce aneuploidy and spontaneous transformation of mouse. Cell Cycle 11(15), 2864-2875, 2012 (IF=3.952; NC=44)
32. Zhang Y,Xu B,Yang Y,Ban R,Zhang H,Jiang X,Cooke HJ,Xue Y, Shi Q*. CPSS: a computational platform for the analysis of small RNA deep sequencing data. Bioinformatics 28(14):1925-1927, 2012 (IF=5.766; NC=35)
33. Yang C,Shi X,Huang Y,Zhang Z,Cooke HJ,Wang M,Shi Q*. Rapid proliferation of daughter cells lacking particular chromosomes due to multipolar mitosis promotes clonal evolution in colorectal cancer cells. Cell Cycle 11(14):2650-9, 2012 (IF=3.952;NC=3)
34. Hou H, Zhang Y, Huang Y, Yi Q, Lv L, Zhang T, Chen D, Hao Q, Shi Q*. Inhibitors of phosphatidylinositol 3'-kinases promote mitotic cell death in HeLa cells. PLoS One 7(4):e35665, 2012 (IF=3.057; NC=35)
35. Huang Y, Jiang L, Yi Q, Lv L, Wang Z, Zhao X, Zhong L, Jiang H, Rasool S, Hao Q, Guo Z, Cooke HJ, Fenech M, Shi Q*. Lagging chromosomes entrapped in micronuclei are not 'lost' by cells. Cell Res 22(5):932-5, 2012 Feb 21.(IF=14.812; NC=17)
36. Pan Z, Yang Q, Ye N, Wang L, Li J, Yu D, Cooke HJ, Shi Q*. Complex relationship between meiotic recombination frequency and autosomal synaptonemal complex length per cell in normal human males. Am J Med Genet A 158A(3):581-7, 2012 (IF=2.082;NC=12)
37. Chao H, Zhang X, Chen B, Pan B, Zhang L, Li L, Sun X, Shi Q,Shen W. Bisphenol A exposure modifies methylation of imprinted genes in mouse oocytes via the estrogen receptor signaling pathway. Histochem Cell Biol 2012 137:249-259. (IF=2.78;NC=70)
38. Chen D, Zhang Y, Yi Q, Huang Y, Hou H, Zhang Y, Hao Q, Cooke HJ, Li L, Sun Q, Shi Q*. Regulation of Asymmetrical Cytokinesis by cAMP during Meiosis I in Mouse Oocytes.  PLoS One 7(1):e29735, 2012 (IF=3.057 ;NC=5)
39. Yi Q, Zhao X, Huang Y, Ma T, Zhang Y, Hou H, Cooke HJ, Yang DQ, Wu M, Shi Q*. p53 dependent centrosome clustering prevents multipolar mitosis in tetraploid cells.  PLoS One 6(11):e27304, 2011 (IF=3.057; NC=21)
40. Chen Q, Shi X, Rudolph C, Yu Y, Zhang D, Zhao X, Mai S, Wang G, Schlegelberger B, Shi Q*. Recurrent trisomy and Robertsonian translocation of chromosome 14 in murine iPS cell lines.  Chromosome Res 19(7):857-68, 2011 (IF=2.59; NC=16)
41.Yang Q, Zhang D, Leng M, Yang L, Zhong L, Cooke HJ, Shi Q*. Synapsis and meiotic recombination in male Chinese muntjac (Muntiacus reevesi).  PLoS One 6(4):e19255, 2011 (IF=3.057; NC=12)
42.Huang Y, Hou H, Yi Q, Zhang Y, Chen D, Jiang E, Xia Y, Fenech M, Shi Q * . The fate of micronucleated cells post X-irradiation detected by live cell imaging.  DNA Repair 10:629-38, 2011 (IF=3.929; NC=22)
43.Zhang Y, Yang Y, Zhang H, Jiang X, Xu B, Xue Y, Cao Y, Zhai Q, Zhai Y, Xu M, Cooke HJ, Shi Q*. Prediction of novel pre-microRNAs with high accuracy through boosting and SVM.  Bioinformatics 27(10):1436-7, 2011 (IF=5.766; NC=30)
44.Xu B, Hua J, Zhang Y, Jiang X, Zhang H, Ma T, Zheng W, Sun R, Shen W, Sha J, Cooke HJ, Shi Q*. Proliferating cell nuclear antigen (PCNA) regulates primordial follicle assembly by promoting apoptosis of oocytes in fetal and neonatal mouse ovaries.  PLoS One 6(1):e16046, 2011 (IF=3.057; NC=61)
45.Huang Y, Shi Q*.Micronucleus formation detected by live-cell imaging.  Mutagenesis 26(1):133-8, 2011 (IF=2.297; NC=16)
46.Cai X, Li J, Yang Q, Shi Q*. Gamma-irradiation increased meiotic crossovers in mouse spermatocytes.Mutagenesis.26(6):721-7, 2009 (IF=2.297;NC=6)
47.Xu W, Chen J, Chen H, Diao R, Fok K, Dong J, Sun T, Chen W, Yu M, Zhang X, Tsang L, Lau A, Shi Q, Huang P, Chan H. Defective CFTR-dependent CREB activation results in impaired spermatogenesis and azoospermia. PLoS One. 2011, 6: e19120. ( IF=3.057;NC=47)
48.Wang G, Gao X, Huang Y, Yao Z, Shi Q,Wu M. Nucleophosmin/B23 inhibits Eg5-mediated microtubule depolymerization by inactivating its ATPase activity. J Biol Chem, 2010, 285:19060-7. (IF=4.258;NC=17)
49.Zhang P, Chao H, Sun X, Li L, Shi Q,Shen W. Murine folliculogenesis in vitro is stage-specifically regulated by insulin via the Akt signaling pathway. Histochem Cell Biol. 2010, 134: 75-82. (IF=2.78;NC=18)
50.Sun L, Sun Z, Zhang P, Zhai X, Tang J, Pan Q, Shi Q,Shen W. Effect of insulin on oogenesis from mouse fetal germ cells in a serum-free 3D culture system. Reproductive BioMedicine Online. 2010, 20: 11-25. (IF=2.796;NC=15)
51.Song L, Li J, Liao W, Feng Y, Yu C, Hu L, Kong Q, Xu L, Zhang X, Liu W, Li M, Zhang L, Kang T, Fu L, Huang W, Xia Y, Tsao S, Li M, Band V, Band H, Shi Q, Zeng Y, Zeng M. The polycomb group protein Bmi-1 represses the tumor suppressor PTEN and induces epithelial-mesenchymal transition in human nasopharyngeal epithelial cells. Journal of Clinical Investigation 2009, 119:3626-36. (IF=12.575;NC=312)
52.Song Y, Chen Q, Zhang Z, Hou H, Zhang D, Shi Q*. Effects of age on segregation of the X and Y chromosomes in cultured lymphocytes from Chinese men. Journal of Genetics and Genomics 2009, 36: 467-474. (IF=3.981;NC=3)
53.Leng M, Li G, Zhong L, Hou H, Yu D, Shi Q*. Abnormal synapses and recombination in an azoospermic male carrier of a reciprocal translocation t(1;21).Fertil Steril Apr;91(4):1293.e17-22. 2009(IF=4.426,NC=20)
54.Song Z, Min L, Pan Q, Shi Q, Shen W. Maternal imprinting during mouse oocyte growth in vivo and in vitro. Biochem Biophys Res Commun. 2009 387: 800-805. (IF=2.371;NC=20)
55.Wang N, Zhang P, Guo X, Xie J, Huo R, Wang F, Chen L, Shen J, Zhou Z, Shi Q*, Zhao B, Sha J. Comparative proteome profile of immature rat ovary during primordial follicle assembly and development.Proteomics 2009, 9: 3425-3434. (IF=4.079;NC=14)
56.Dong H, Li L, Song Z, Tang J, Xuc B, Zhai X, Sun L, Zhang P, Li Z, Pan Q, Shi Q*, Shen W. Premeiotic fetal murine germ cells cultured in vitro form typical oocyte-like cells but do not progress through meiosis. Theriogenology 2009 72: 219–231. (IF=1.838;NC=18)
57.Rao X, Zhang Y, Yi Q, Hou H, Xu B, Chu L, Huang Y, Zhang W, Fenech M, Shi Q* .Multiple origins of spontaneously arising micronuclei in HeLa cells: direct evidence from long-term live cell imaging. Mutat Res 646(1-2):41-9, 2008 (IF=2.581; NC=50)
58.Yan X, Cao L, Li Q, Wu Y, Zhang H, Saiyin H, Liu X, Zhang X, Shi Q* ,Yu L. Aurora C is directly associated with Survivin and required for cytokinesis. Genes Cells 2005 10: 617-626(IF=2.481;NC=125)
59. Li JH, Leng M, Ma TL, Yu DX, Shi QH*. Cryopreservation has no effect on meiotic recombination and synapsis in testicular tissues. Fertil Steril Apr;91(4 Suppl):1404-7. 2009 (IF=4.426,NC=8)
60. Shi Q, Spriggs E, Field L, Rademaker A, Ko E, Barclay L, Martin RH.Absence of age effect on meiotic recombination between human X and Y chromosomes. Am J Hum Genet 50.2002 71: 254-261. (IF=10.794;NC=26)
61 Martin RH, Shi Q*, Field LL. Recombination in the pseudoautosomal region in a 47, XYY male. Hum Genet 2001 109: 143-145. (IF=5.138;NC=10)
63 Shi Q, Spriggs E, Field LL, Ko E, Barclay L, Martin RH.Single sperm typing demonstrates that reduced recombination is associated with the production of aneuploid 24,XY human sperm Am J Med Genet 2001 99: 34-38(IF=2.082;NC=93).
66 Shi Q, Martin RH. Increased nondisjunction of chromosome 21 with age in human peripheral lymphocytes. Mutat Res 2000 452: 27-36. (IF=2.581;NC=24)
70 Shi Q, Adler ID. Colcemid and econazole do not show aneugenicity in male mouse germ cells. Mutagenesis 1998 13(4):409-16. (IF=2.297;NC=6)
Copyright @中国科学技术大学分子细胞遗传学实验室