1. Fan S, Jiao Y, Khan R, Jiang X, Javed AR, Ali A, Zhang H, Zhou J, Naeem M, Murtaza G, Li Y, Yang G, Zaman Q, Zubair M, Guan H, Zhang X, Ma H, Jiang H, Ali H, Dil S, Shah W, Ahmad N, Zhang Y*, Shi Q*. Homozygous mutations in C14orf39/SIX6OS1 cause non-obstructive azoospermia and premature ovarian insufficiency in humans. Am J Hum Genet 2021;108(2):324-336 .

20.Hinch AG, Becker PW, Li T, Moralli D, Zhang G, Bycroft C, Green C, Keeney S, Shi Q , Davies B, Donnelly P*. The Configuration of RPA, RAD51, and DMC1 Binding in Meiosis Reveals the Nature of Critical Recombination Intermediates Mol Cell. 2020 Aug 20; 79(4):689-701.e10

21.Wang Y, Wang H, Zhang Y, Du Z, Si W, Fan S, Qin D, Wang M, Duan Y, Li L, Jiao Y, Li Y, Wang Q, Shi Q,Wu X*, Xie W* Reprogramming of Meiotic Chromatin Architecture during Spermatogenesis. Mol Cell 2019 Feb 7;73(3):547-561.

22. Yin H, Ma H, Hussain S, Zhang H, Xie X, Jiang L, Jiang X, Iqbal F, Bukhari I, Jiang H, Ali A, Zhong L, Li T, Fan S, Zhang B, Gao J, Li Y, Nazish J, Khan T, Khan M, Zubair M, Hao Q, Fang H, Huang J, Huleihel M, Sha J, Pandita TK, Zhang Y*, Shi Q*. A homozygous FANCM frameshift pathogenic variant causes male infertility. Genet Med. 2019;21(1):62-70.

23. Jiang X, Yin S, Fan S, Bao J, Jiao Y, Ali A, Iqbal F, Xu J, Zhang Y*, Shi Q*. Npat-dependent programmed Sertoli cell proliferation is indispensable for testis cord development and germ cell mitotic arrest. FASEB J 2019;33(8):9075-86.

24. Yang X, Zhang X, Jiao J, Zhang F, Pan Y, Wang Q, Chen Q, Cai B, Tang S, Zhou Z, Chen S, Yin H, Fu W, Luo Y, Li D, Li G, Shang L, Yang J, Jin L, Shi Q*, Wu Y*.Rare variants in FANCA induce premature ovarian insufficiency. Hum Genet 2019;138(11-12):1227-36.

25. Zheng W, Nazish J, Wahab F, Khan R, Jiang X, Shi Q*. DDB1 Regulates Sertoli Cell Proliferation and Testis Cord Remodeling by TGFβ Pathway Genes (Basel). 2019 Nov 26;10(12). pii: E974. doi: 10.3390/genes10120974.

26. Huang Z, Khan M, Xu J, Khan T, Ma H, Khan R, Hussain HMJ, Jiang X*, Howard J Cooke*, Shi Q*. The deubiquitinating gene Usp29 is dispensable for fertility in male mice. Sci China Life Sci 2019;62(4):544-52.

27.Xie Y, Khan R, Wahab F, Hussain HMJ, Ali A, Ma H, Jiang H, Xu J, Zaman Q, Khan M, Jiang X*,Shi Q*. The testis-specifically expressed Dpep3 is not essential for male fertility in mice. Gene 2019;711:143925.

28. Shi B, Xue J, Yin H, Guo R, Luo M, Ye L, Shi Q, Huang X, Liu M, Sha J*, Wang PJ*. Dual functions for the ssDNA-binding protein RPA in meiotic recombination. PLoS Genet 28.2019;15(2):e1007952.

29. Zhang H, Ali A, Gao J, Ban R, Jiang X*, Zhang Y*, Shi Q*.IsopiRBank: a research resource for tracking piRNA isoforms Database (Oxford) . 2018;

30. Khan M, Jabeen N, Khan T, Hussain HMJ, Ali A, Khan R, Jiang L, Li T, Tao Q, Zhang X, Yin H, Yu C, Jiang X*, Shi Q* . The evolutionarily conserved genes: Tex37, Ccdc73, Prss55 and Nxt2 are dispensable for fertility in mice. Sci Rep. 2018;8(1):4975

31.Jiang H, Gao Q, Zheng W, Yin S, Wang L, Zhong L, Ali A, Khan T, Hao Q, Fang H, Sun X, Xu P, Pandita TK, Jiang X*, Shi Q* MOF influences meiotic expansion of H2AX phosphorylation and spermatogenesis in mice. PLoS Genet.2018 May 24;14(5):e1007300. doi: 10.1371/journal.pgen.1007300.

32. Bao J, Perez CJ, Kim J, Zhang H, Murphy CJ, Hamidi T, Jaubert J, Platt CD, Chou J, Deng M, Zhou MH, Huang Y, Gaitan-Penas H, Guenet JL, Lin K, Lu Y, Chen T, Bedford MT, Dent SY, Richburg JH, Estevez R, Pan HL, Geha RS,Shi Q , Benavides F*Deficient LRRC8A-dependent volume-regulated anion channel activity is associated with male infertility in mice. JCI insight 2018;3(16).

33.AbuMadighem A, Solomon R, Stepanovsky A, Kapelushnik J, Shi Q, Meese E, Lunenfeld E, Huleihel M*. Development of Spermatogenesis In Vitro in Three-Dimensional Culture from Spermatogonial Cells of Busulfan-Treated Immature Mice. Int J Mol Sci . 33.Int J Mol Sci 2018;19(12).

34. Abofoul-Azab M, AbuMadighem A, Lunenfeld E, Kapelushnik J, Shi Q, Pinkas H, Huleihel M*. Development of Postmeiotic Cells In Vitro from Spermatogonial Cells of Prepubertal Cancer Patients.  Stem Cells Dev 2018;27(15):1007-20.

35. Shi B, Xue J, Zhou J, Kasowitz SD, Zhang Y, Liang G, Guan Y, Shi Q,Liu M, Sha J, Huang X*, Wang PJ*MORC2B is essential for meiotic progression and fertility.  PLoS Genet 2018;14(1):e1007175.

36.Jiang L, Li T, Zhang X, Zhang B, Yu C, Li Y, Fan S, Jiang X, Khan T, Hao Q, Xu P, Nadano D, Huleihel M, Lunenfeld E, Wang PJ, Zhang Y*, Shi Q*. RPL10L Is Required for Male Meiotic Division by Compensating for RPL10 during Meiotic Sex Chromosome Inactivation in Mice Curr Biol. 2017 27(10):1498-1505.

37. Yin S, Jiang X, Jiang H, Gao Q, Wang F, Fan S, Khan T, Jabeen N, Khan M, Ali A, Xu P, Pandita TK, Fan HY, Zhang Y, Shi Q*. Histone acetyltransferase KAT8 is essential for mouse oocyte development by regulating ROS levels. Development. 37.2017 144(12): 2165-2174.

38.Zhang T, Lv L, Huang Y, Ren X,Shi Q* Chromosome nondisjunction during bipolar mitoses of binucleated intermediates promote aneuploidy formation along with multipolar mitoses rather than chromosome loss in micronuclei induced by asbestos. Oncotarget. 2017 Feb 14;8(7):11030-11041. doi: 10.18632/oncotarget.14212.

39. Pan H, Zhang X, Jiang H, Jiang X, Wang L, Qi Q, Bi Y, Wang J, Shi Q*, Li R*. Ndrg3 gene regulates DSB repair during meiosis through modulation the ERK signal pathway in the male germ cells. Sci Rep. 2017 Mar 14;7:44440. doi: 10.1038/srep44440.

40. Liu C, Li M, Li T, Zhao H, Huang J, Wang Y, Gao Q, Yu Y*, Shi Q*. ECAT1 is essential for human oocyte maturation and pre-implantation development of the resulting embryos. Sci Rep. 2016 Dec 5;6:38192. doi: 10.1038/srep38192.

48. Chu B, Zhong L, Dou S, Wang J, Li J, Wang M, Shi Q* , Mei Y* , Wu M*. miRNA-181 regulates embryo implantation in mice through targeting leukemia inhibitory factor. Mol Cell Biol 7(1):12-22,2015.

49.Wang L, Xu Z, Iqbal F, Zhong L, Zhang Y, Wu C, Zhou G, Jiang H, Bukhari I, Cooke HJ, Shi Q*. Decreased XY recombination and disturbed meiotic prophase I progression in an infertile 48, XYY, +sSMC man. Chromosome Res 23(2):267-76,2015

50. Jiang X, Ma T, Zhang Y, Zhang H, Yin S, Zheng W, Wang L, Wang Z, Khan M, Sheikh SW, Bukhari I, Iqbal F, Cooke HJ, Shi Q*. Specific Deletion of Cdh2 in Sertoli Cells Leads to Altered Meiotic Progression and Subfertility of Mice. Biology of Reproduction 92(3):1-12,2015

51. Hua J, Xu B, Yang Y, Ban R, Iqbal F, Cooke HJ, Zhang Y*, Shi Q*. Follicle Online: an integrated database of follicle assembly, development and ovulation. Database (Oxford). 2015 Apr 29; 2015:bav036.

52. Wang L, Iqbal F, Li G, Jiang X, Bukhari I, Jiang H, Yang Q, Zhong L, Zhang Y, Hua J, Cooke HJ, Shi Q*. Abnormal meiotic recombination with complex chromosomal rearrangement in an azoospermic man. Reprod Biomed Online. 30(6):651-8,2015.

53. Gao X, Ma W, Nie J, Zhang C, Zhang J, Yao G, Han J, Xu J, Hu B, Du Y, Shi Q,Yang Z, Huang X*,Zhang Y*. A G-quadruplex DNA structure resolvase, RHAU, is essential for spermatogonia differentiation. Cell Death Dis 2015 Jan 22;6:e1610.

54. Wang Z, Yin H, Zhang Y, Feng Y, Yan Z, Jiang X, Bukhari I, Iqbal F, Cooke HJ, Shi Q*. miR-214-mediated downregulation of RNF8 induces chromosomal instability in ovarian cancer cells Cell Cycle 13(2):3519-3528,2014.

55. Jiang X, Zhang H, Yin S, Zhang Y, Yang W, Zheng W, Wang L, Wang Z, Bukhari I, Cooke HJ,Iqbal F*, Shi Q*. Specific deficiency of Plzf paralog, Zbtb20, in Sertoli cells does not affect spermatogenesis and fertility in mice. Sci Rep 4:7062, 2014.

56. Ma H, Cooke HJ, Shi Q*. Meiosis: Recent Progress and New Opportunities J Genet Genomics 41(3):83-5,2014.

57. Jiang H, Wang L, Cui Y, Xu Z, Guo T, Cheng D, Xu P, Yu W, Shi Q*. Meiotic Chromosome Behavior in a Human Male t(8;15) Carrier. J Genet Genomics. 2014, 41(3):177-85. doi: 10.1186/1755-8166-7-45.

58. Yao Q, Wang L, Yao B, Gao H, Li W, Xia X, Shi Q , Cui Y*. Meiotic prophase I defects in an oligospermic man with Wolf-Hirschhorn syndrome with ring chromosome 4. Mol Cytogenet. 2014, 7:45. doi: 10.1186/1755-8166-7-45.

59. Wang J, Qian J, Hu Y, Kong X, Chen H , Shi Q ,Jiang L, Wu C, Zou W, Chen Y, Xu J, Fang JY*. ArhGAP30 promotes p53 acetylation and function in colorectal cancer. Nat Commun. 2014, 5:4735.

60. Jiang XH, Bukhari I, Zheng W, Yin S, Wang Z, Cooke HJ, Shi Q* . Blood-testis barrier and spermatogenesis: lessons from genetically-modified mice Asian J Androl 16(4):572-80,2014

61. Zhang H, Jiang X, Zhang Y, Xu B, Hua J, Ma T, Zheng W, Sun R, Shen W, Cooke HJ, Hao Q, Qiao J, Shi Q*. microRNA 376a regulates follicle assembly by targeting Pcna in fetal and neonatal mouse ovaries hybrid cells Reproduction 148(1):43-54,2014

62. Wang Z, Yin H, Lv L, Feng Y, Chen S, Liang J, Huang Y, Jiang X, Jiang H, Bukhari I, Wu L, Cooke HJ, Shi Q*. Unrepaired DNA damage facilitates elimination of uniparental chromosomes in interspecific hybrid cells Cell Cycle 13(8):1345-56,2014

63. Yang Q, Hua J, Wang L, Xu B, Zhang H, Ye N, Zhang Z, Yu D, Cooke HJ, Zhang Y, Shi Q *. MicroRNA and piRNA Profiles in Normal Human Testis Detected by Next Generation Sequencing Plos One 8(6):e66809, 2013

64. Wu J, Liu Q, Wang X, Zheng J, Sheng Sun Z, Shi Q*. mirTools 2.0 for non-coding RNA discovery, profiling and functional annotation based on high-throughput sequencing RNA Biol 10(7), 2013

65. Zhang Y, Zhong L, Xu B, Yang Y, Ban R, Zhu J, Cooke HJ, Hao Q, Shi Q*. SpermatogenesisOnline 1.0: a resource for spermatogenesis based on manual literature curation and genome-wide data mining. Nucleic Acids Res 41:D1055-62,2013

66. Wang XX, Ying P, Diao F, Wang Q, Ye D, Jiang C, Shen N, Xu N, Chen WB, Lai SS, Jiang S, Miao XL, Feng J, Tao WW, Zhao NW, Yao B, Xu ZP, Sun HX, Li JM, Sha JH, Huang XX, Shi Q,Tang H, Gao X*,Li CJ*. Altered protein prenylation in Sertoli cells is associated with adult infertility resulting from childhood mumps infection. J Exp Med. 2013, 210(8):1559-74.

67. Lv L, Zhang T, Yi Q, Huang Y, Wang Z, Hou H, Zhang H, Zhang W, Hao Q, Guo Z, Cooke HJ, Shi Q*. Tetraploid cells from cytokinesis failure induce aneuploidy and spontaneous transformation of mouse. Cell Cycle 11(15), 2864-2875, 2012

68. Zhang Y, Xu B, Yang Y, Ban R, Zhang H, Jiang X, Cooke HJ, Xue Y, Shi Q*. CPSS: a computational platform for the analysis of small RNA deep sequencing data. Bioinformatics 28(14):1925-1927, 2012

69. Yang C, Shi X, Huang Y, Zhang Z, Cooke HJ, Wang M, Shi Q*. Rapid proliferation of daughter cells lacking particular chromosomes due to multipolar mitosis promotes clonal evolution in colorectal cancer cells. Cell Cycle 11(14):2650-9, 2012

70. Hou H, Zhang Y, Huang Y, Yi Q, Lv L, Zhang T, Chen D, Hao Q, Shi Q*. Inhibitors of phosphatidylinositol 3'-kinases promote mitotic cell death in HeLa cells. PLoS One 7(4):e35665, 2012

71. Huang Y, Jiang L, Yi Q, Lv L, Wang Z, Zhao X, Zhong L, Jiang H, Rasool S, Hao Q, Guo Z, Cooke HJ, Fenech M, Shi Q*. Lagging chromosomes entrapped in micronuclei are not 'lost' by cells. Cell Res 22(5):932-5, 2012 Feb 21.

72. Pan Z, Yang Q, Ye N, Wang L, Li J, Yu D, Cooke HJ, Shi Q*. Complex relationship between meiotic recombination frequency and autosomal synaptonemal complex length per cell in normal human males. Am J Med Genet A 158A(3):581-7, 2012

73. Chao H, Zhang X, Chen B, Pan B, Zhang L, Li L, Sun X, Shi Q,Shen W*. Bisphenol A exposure modifies methylation of imprinted genes in mouse oocytes via the estrogen receptor signaling pathway. Histochem Cell Biol 2012 137:249-259.

74. Chen D, Zhang Y, Yi Q, Huang Y, Hou H, Zhang Y, Hao Q, Cooke HJ, Li L, Sun Q, Shi Q*. Regulation of Asymmetrical Cytokinesis by cAMP during Meiosis I in Mouse Oocytes.  PLoS One 7(1):e29735, 2012

75. Yi Q, Zhao X, Huang Y, Ma T, Zhang Y, Hou H, Cooke HJ, Yang DQ, Wu M, Shi Q*. p53 dependent centrosome clustering prevents multipolar mitosis in tetraploid cells.  PLoS One 6(11):e27304, 2011

76. Chen Q, Shi X, Rudolph C, Yu Y, Zhang D, Zhao X, Mai S, Wang G, Schlegelberger B, Shi Q*. Recurrent trisomy and Robertsonian translocation of chromosome 14 in murine iPS cell lines.  Chromosome Res 19(7):857-68, 2011

77. Yang Q, Zhang D, Leng M, Yang L, Zhong L, Cooke HJ, Shi Q*. Synapsis and meiotic recombination in male Chinese muntjac (Muntiacus reevesi).  PLoS One 6(4):e19255, 2011

78. Huang Y, Hou H, Yi Q, Zhang Y, Chen D, Jiang E, Xia Y, Fenech M, Shi Q * . The fate of micronucleated cells post X-irradiation detected by live cell imaging.  DNA Repair 10:629-38, 2011

79. Zhang Y, Yang Y, Zhang H, Jiang X, Xu B, Xue Y, Cao Y, Zhai Q, Zhai Y, Xu M, Cooke HJ, Shi Q*. Prediction of novel pre-microRNAs with high accuracy through boosting and SVM.  Bioinformatics 27(10):1436-7, 2011

80. Xu B, Hua J, Zhang Y, Jiang X, Zhang H, Ma T, Zheng W, Sun R, Shen W, Sha J, Cooke HJ, Shi Q*. Proliferating cell nuclear antigen (PCNA) regulates primordial follicle assembly by promoting apoptosis of oocytes in fetal and neonatal mouse ovaries.  PLoS One 6(1):e16046, 2011

81. Huang Y, Shi Q*.Micronucleus formation detected by live-cell imaging.  Mutagenesis 26(1):133-8, 2011

82. Cai X, Li J, Yang Q, Shi Q*. Gamma-irradiation increased meiotic crossovers in mouse spermatocytes.Mutagenesis.26(6):721-7, 2009

83. Xu W, Chen J, Chen H, Diao R, Fok K, Dong J, Sun T, Chen W, Yu M, Zhang X, Tsang L, Lau A, Shi Q, Huang P, Chan H*. Defective CFTR-dependent CREB activation results in impaired spermatogenesis and azoospermia. PLoS One. 2011, 6: e19120.

84. Wang G, Gao X, Huang Y, Yao Z, Shi Q*,Wu M*. Nucleophosmin/B23 inhibits Eg5-mediated microtubule depolymerization by inactivating its ATPase activity. J Biol Chem, 2010, 285:19060-7.

85. Zhang P, Chao H, Sun X, Li L, Shi Q,Shen W*. Murine folliculogenesis in vitro is stage-specifically regulated by insulin via the Akt signaling pathway. Histochem Cell Biol. 2010, 134: 75-82.

86. Sun L, Sun Z, Zhang P, Zhai X, Tang J, Pan Q, Shi Q,Shen W*. Effect of insulin on oogenesis from mouse fetal germ cells in a serum-free 3D culture system. Reprod Biomed Online. 2010, 20: 11-25.

87. Song L, Li J, Liao W, Feng Y, Yu C, Hu L, Kong Q, Xu L, Zhang X, Liu W, Li M, Zhang L, Kang T, Fu L, Huang W, Xia Y, Tsao S, Li M, Band V, Band H, Shi Q, Zeng Y, Zeng M*. The polycomb group protein Bmi-1 represses the tumor suppressor PTEN and induces epithelial-mesenchymal transition in human nasopharyngeal epithelial cells. J Clin Invest 2009, 119:3626-36.

88. Song Y, Chen Q, Zhang Z, Hou H, Zhang D, Shi Q*. Effects of age on segregation of the X and Y chromosomes in cultured lymphocytes from Chinese men. J Genet Genomics. 2009, 36: 467-474.

89. Leng M, Li G, Zhong L, Hou H, Yu D, Shi Q*. Abnormal synapses and recombination in an azoospermic male carrier of a reciprocal translocation t(1;21).Fertil Steril Apr;91(4):1293.e17-22. 2009

90. Song Z, Min L, Pan Q, Shi Q, Shen W*. Maternal imprinting during mouse oocyte growth in vivo and in vitro. Biochem Biophys Res Commun. 2009 387: 800-805.

91. Wang N, Zhang P, Guo X, Xie J, Huo R, Wang F, Chen L, Shen J, Zhou Z, Shi Q, Zhao B, Sha J*. Comparative proteome profile of immature rat ovary during primordial follicle assembly and development.Proteomics 2009, 9: 3425-3434.

92. Dong H, Li L, Song Z, Tang J, Xuc B, Zhai X, Sun L, Zhang P, Li Z, Pan Q, Shi Q*, Shen W*. Premeiotic fetal murine germ cells cultured in vitro form typical oocyte-like cells but do not progress through meiosis. Theriogenology 2009 72: 219–231.

93. Li JH, Leng M, Ma TL, Yu DX, Shi QH*. Cryopreservation has no effect on meiotic recombination and synapsis in testicular tissues. Fertil Steril Apr;91(4 Suppl):1404-7. 2009

94. Rao X, Zhang Y, Yi Q, Hou H, Xu B, Chu L, Huang Y, Zhang W, Fenech M, Shi Q* .Multiple origins of spontaneously arising micronuclei in HeLa cells: direct evidence from long-term live cell imaging. Mutat Res 646(1-2):41-9, 2008

95. Yan X, Cao L, Li Q, Wu Y, Zhang H, Saiyin H, Liu X, Zhang X, Shi Q ,Yu L*. Aurora C is directly associated with Survivin and required for cytokinesis. Genes Cells 2005 10: 617-626

96. Shi Q, King RW*. Chromosome nondisjunction yields tetraploid rather than aneuploid cells in human cell lines. Nature 2005 437: 1038-1042.

97. Shi Q, Spriggs E, Field L, Rademaker A, Ko E, Barclay L, Martin RH*.Absence of age effect on meiotic recombination between human X and Y chromosomes. Am J Hum Genet 50.2002 71: 254-261.

98. Martin RH, Shi Q*, Field LL. Recombination in the pseudoautosomal region in a 47, XYY male. Hum Genet 2001 109: 143-145.

99. Shi Q, Martin RH*. Aneuploidy in human spermatozoa: FISH analysis in men with constitutional chromosomal abnormalities, and in infertile men. Reproduction 52. 121: 655-666.

100. Shi Q, Spriggs E, Field LL, Ko E, Barclay L, Martin RH*.Single sperm typing demonstrates that reduced recombination is associated with the production of aneuploid 24,XY human sperm Am J Med Genet 2001 99: 34-38.

101. Shi Q, Adler ID,Zhang JX,Zhang XR,Shan XN,Martin RH*. Incidence of mosaic cell lines in vivo and malsegregation of chromosome 21 in lymphocytes in vitro of trisomy 21 patients: detection by fluorescence in situ hybridization on binucleated lymphocytes. Hum Genet 54.2000 106: 29-35.

102. Shi Q, Martin RH*. Multicolor fluorescence in situ hybridization analysis of meiotic chromosome segregation in a 47,XYY male and a review of the literature. Am J Med Genet 2000 936: 40-46.

103. Shi Q, Martin RH*. Increased nondisjunction of chromosome 21 with age in human peripheral lymphocytes. Mutat Res 2000 452: 27-36.

104. Shi Q, Martin RH*. Spontaneous frequencies of aneuploid and diploid sperm in 10 normal Chinese men: assessed by multicolor fluorescence in situ hybridization. Cytogenet Cell Genet 2000 90: 79-83.

105. Shi Q, Martin RH*. Aneuploidy in human sperm: a review of the frequency and distribution of aneuploidy, effects of donor age and lifestyle factors. Cytogenet Cell Genet 58.2000 90: 219-226.

106. Shi Q, Schmid TE*, Adler ID. Griseofulvin-induced aneuploidy and meiotic delay in male mouse germ cells: detected by using conventional cytogenetics and three-color FISH. Mutat Res 1999 441: 181-190

107. Shi Q, Adler ID*. Colcemid and econazole do not show aneugenicity in male mouse germ cells. Mutagenesis 1998 13(4):409-16.