Molecular&Cell Genetics Laboratory
Mol&Cell Genet
English Version
主要论文(*:corresponding author)
1. Fan S, Jiao Y, Khan R, Jiang X, Javed AR, Ali A, Zhang H, Zhou J, Naeem M, Murtaza G, Li Y, Yang G, Zaman Q, Zubair M, Guan H, Zhang X, Ma H, Jiang H, Ali H, Dil S, Shah W, Ahmad N, Zhang Y*, Shi Q*. Homozygous mutations in C14orf39/SIX6OS1 cause non-obstructive azoospermia and premature ovarian insufficiency in humans. Am J Hum Genet 2021;108(2):324-336 .
2. Liu C, Tu C, Wang L, Wu H, Houston BJ, Mastrorosa FK, Zhang W, Shen Y, Wang J, Tian S, Meng L, Cong J, Yang S, Jiang Y, Tang S, Zeng Y, Lv M, Lin G, Li J, Saiyin H, He X, Jin L, Touré A, Ray PF, Veltman JA, Shi Q, O'Bryan MK, Cao Y, Tan YQ*, Zhang F*. Deleterious variants in X-linked CFAP47 induce asthenoteratozoospermia and primary male infertility. Am J Hum Genet. 2021 Feb 4;108(2):309-323.

3. Ma H, Zhang B, Khan A, Zhao D, Ma A, Jianteng Z, Khan I, Khan K, Zhang H, Zhang Y, Xiaohua J, Dil S, Zeb A, Rahim F, Shi Q*. Novel frameshift mutation in STK33 is associated with asthenozoospermia and multiple morphological abnormality of the flagella. Hum Mol Genet. 2021 Jun 21:ddab165. doi: 10.1093/hmg/ddab165.

4. Shah B, Khan R, Shah W, Aftab A, Khan M, Dil S, Shi Q*. Inactivation of testis-specific gene C4orf46 is dispensable for spermatogenesis and fertility in mouse. Mamm Genome. 2021 Jun 2. d oi: 10.1007/s00335-021-09879-z.

5. Khan I, Shah B, Dil S, Ullah N, Zhou JT, Zhao DR, Zhang YW, Jiang XH, Khan R, Khan A, Ali H, Zubair M, Shah W, Zhang H*, Shi QH*. Novel biallelic loss-of-function mutations in CFAP43 cause multiple morphological abnormalities of the sperm flagellum in Pakistani families Asian J Androl. 2021 May 28

6. Guo TH, Sang MY, Bai S, Ma H, Wan YY, Jiang XH, Zhang YW, Xu B, Chen H, Zheng XY, Luo SH, Xie XF, Gong CJ, Weng JP*, Shi QH*, Semen parameters in men recovered from COVID-19.   Asian J Androl. 2021 May 11. doi: 10.4103/aja.aja_31_21.

7. Li Y, Wu Y, Zhou J, Zhang H, Zhang Y, Ma H, Jiang X*, Shi Q*. A recurrent ZSWIM7 mutation causes male infertility resulting from decreased meiotic recombination. Hum Reprod. 2021 Apr 20;36(5):1436-1445

8. Dai XX, Jiang Y, Gu JH, Jiang ZY, Wu YW, Yu C, Yin H, Zhang J, Shi Q, Shen L, Sha QQ, Fan HY, . The CNOT4 Subunit of the CCR4-NOT Complex is Involved in mRNA Degradation, Efficient DNA Damage Repair, and XY Chromosome Crossover during Male Germ Cell Meiosis. Adv Sci (Weinh).2021 Mar 16;8(10):2003636. doi: 10.1002/advs.202003636.

9. Li Y, Wu YF, Jiang HW, Khan R, Han QQ, Iqbal F, Jiang XH*, Shi QH* The molecular control of meiotic double-strand break (DSB) formation and its significance in human infertility.  Asian J Androl. 2021 Feb 12. doi: 10.4103/aja.aja_5_21

10. Khan R, Jiang X, Hameed U, Shi Q*. Role of Lipid Metabolism and Signaling in Mammalian Oocyte Maturation, Quality, and Acquisition of Competence. Front Cell Dev Biol 2021 Mar 5;9:639704. doi: 10.3389/fcell.2021.639704

11. Zaman Q, Khan R, Hameed U, Shah W, Waqas A, Zubair M, Dil S, Zafar T, Ali A, Unar A, Shi Q*. Exonuclease 5 is dispensable for meiotic progression and male fertility in mouse.  Gene. 2021 Feb 15;769:145254. doi: 10.1016/j.gene.2020.145254.

12. Zhang B, Ma H, Khan T, Ma A, Li T, Zhang H, Gao J, Zhou J, Li Y, Yu C, Bao J, Ali A, Murtaza G, Yin H, Gao Q, Jiang X, Zhang F, Liu C, Khan I, Zubair M, Hussain HMJ, Khan R, Yousaf A, Yuan L, Lu Y, Xu X, Wang Y, Tao Q, Hao Q, Fang H, Cheng H, Zhang Y*, Shi Q*. A DNAH17 missense variant causes flagella destabilization and asthenozoospermia JEM. 2020, 217(2):e20182365. doi: 10.1084/jem.20182365

13. Zhou J, Gao J, Zhang H, Zhao D, Li A, Iqbal F, Shi Q*, Zhang Y* . PedMiner: a tool for linkage analysis-based identification of disease-associated variants using family based whole-exome sequencing data.  Brief Bioinform 2020.

14. Jiao Y, Fan S, Jabeen N, Zhang H, Khan R, Murtaza G, Jiang H, Ali A, Li Y, Bao J, Zhang B, Xu J, Xu B, Hussain HMJ, Zaman Q, Khan I, Bukhari I, Iqbal F, Yousaf A, Dil S, Khan M, Ahmad N, Ma H, Jiang X, Zhang Y*, Shi Q*. A TOP6BL mutation abolishes meiotic DNA double-strand break formation and causes human infertility. Sci Bull (beijing) 2020.

15. Pan H, Jiang N, Sun S, Jiang H, Xu J, Jiang X, Gao Q, Li L, Wu H, Zheng H, Qi Q, Li T, Zhang M, Zhang L, Wan X, Lin X, Wong J, Shi Q*, Li R* UHRF1-repressed 5'-hydroxymethylcytosine is essential for the male meiotic prophase I Cell Death Dis 2020, 11(2):142.

16. Gao Q, Khan R, Yu C, Alsheimer M, Jiang X, Ma H*,Shi Q* The testis-specific LINC component SUN3 is essential for sperm head shaping during mouse spermiogenesis. J Biol Chem. 295(19):6289-6298.

17.Zhang B, Khan I, Liu C, Ma A, Khan A, Zhang Y, Huan Z, Kakakhel MBS, Zhou J, Zhang W, Li Y, Ali A, Jiang X, Murtaza G, Khan R, Zubair M, Yuan L, Khan M, Wang L, Zhang F, Wang X, Ma H*, Shi Q* Novel loss-of-function variants in DNAH17 cause multiple morphological abnormalities of the sperm flagella in humans and mice.  Clin Genet. 17.2020,99(1):176-186.

18. Cui W, He X, Zhai X, Zhang H, Zhang Y, Jin F, Song X, Wu D, Shi Q, Li L*. CARF promotes spermatogonial self-renewal and proliferation through Wnt signaling pathway.  Cell Discov. 2020 Nov 17; 6(1):85.

19. Gao L, Chang S, Xia W, Wang X, Zhang C, Cheng L, Liu X, Chen L, Shi Q , Huang J, Xu EY*, Shan G*. Circular RNAs from BOULE play conserved roles in protection against stress-induced fertility decline.  Sci Adv. 2020 Nov 11; 6(46):eabb7426.

20.Hinch AG, Becker PW, Li T, Moralli D, Zhang G, Bycroft C, Green C, Keeney S, Shi Q , Davies B, Donnelly P*. The Configuration of RPA, RAD51, and DMC1 Binding in Meiosis Reveals the Nature of Critical Recombination Intermediates Mol Cell. 2020 Aug 20; 79(4):689-701.e10

21.Wang Y, Wang H, Zhang Y, Du Z, Si W, Fan S, Qin D, Wang M, Duan Y, Li L, Jiao Y, Li Y, Wang Q, Shi Q,Wu X*, Xie W* Reprogramming of Meiotic Chromatin Architecture during Spermatogenesis. Mol Cell 2019 Feb 7;73(3):547-561.

22. Yin H, Ma H, Hussain S, Zhang H, Xie X, Jiang L, Jiang X, Iqbal F, Bukhari I, Jiang H, Ali A, Zhong L, Li T, Fan S, Zhang B, Gao J, Li Y, Nazish J, Khan T, Khan M, Zubair M, Hao Q, Fang H, Huang J, Huleihel M, Sha J, Pandita TK, Zhang Y*, Shi Q*. A homozygous FANCM frameshift pathogenic variant causes male infertility. Genet Med. 2019;21(1):62-70.

23. Jiang X, Yin S, Fan S, Bao J, Jiao Y, Ali A, Iqbal F, Xu J, Zhang Y*, Shi Q*. Npat-dependent programmed Sertoli cell proliferation is indispensable for testis cord development and germ cell mitotic arrest. FASEB J 2019;33(8):9075-86.
24. Yang X, Zhang X, Jiao J, Zhang F, Pan Y, Wang Q, Chen Q, Cai B, Tang S, Zhou Z, Chen S, Yin H, Fu W, Luo Y, Li D, Li G, Shang L, Yang J, Jin L, Shi Q*, Wu Y*.Rare variants in FANCA induce premature ovarian insufficiency. Hum Genet 2019;138(11-12):1227-36.
25. Zheng W, Nazish J, Wahab F, Khan R, Jiang X, Shi Q*. DDB1 Regulates Sertoli Cell Proliferation and Testis Cord Remodeling by TGFβ Pathway Genes (Basel). 2019 Nov 26;10(12). pii: E974. doi: 10.3390/genes10120974.
26. Huang Z, Khan M, Xu J, Khan T, Ma H, Khan R, Hussain HMJ, Jiang X*, Howard J Cooke*, Shi Q*. The deubiquitinating gene Usp29 is dispensable for fertility in male mice. Sci China Life Sci 2019;62(4):544-52.
27.Xie Y, Khan R, Wahab F, Hussain HMJ, Ali A, Ma H, Jiang H, Xu J, Zaman Q, Khan M, Jiang X*,Shi Q*. The testis-specifically expressed Dpep3 is not essential for male fertility in mice. Gene 2019;711:143925.
28. Shi B, Xue J, Yin H, Guo R, Luo M, Ye L, Shi Q, Huang X, Liu M, Sha J*, Wang PJ*. Dual functions for the ssDNA-binding protein RPA in meiotic recombination. PLoS Genet 28.2019;15(2):e1007952.
29. Zhang H, Ali A, Gao J, Ban R, Jiang X*, Zhang Y*, Shi Q*.IsopiRBank: a research resource for tracking piRNA isoforms Database (Oxford) . 2018;
30. Khan M, Jabeen N, Khan T, Hussain HMJ, Ali A, Khan R, Jiang L, Li T, Tao Q, Zhang X, Yin H, Yu C, Jiang X*, Shi Q* . The evolutionarily conserved genes: Tex37, Ccdc73, Prss55 and Nxt2 are dispensable for fertility in mice. Sci Rep. 2018;8(1):4975
31.Jiang H, Gao Q, Zheng W, Yin S, Wang L, Zhong L, Ali A, Khan T, Hao Q, Fang H, Sun X, Xu P, Pandita TK, Jiang X*, Shi Q* MOF influences meiotic expansion of H2AX phosphorylation and spermatogenesis in mice. PLoS Genet.2018 May 24;14(5):e1007300. doi: 10.1371/journal.pgen.1007300.
32. Bao J, Perez CJ, Kim J, Zhang H, Murphy CJ, Hamidi T, Jaubert J, Platt CD, Chou J, Deng M, Zhou MH, Huang Y, Gaitan-Penas H, Guenet JL, Lin K, Lu Y, Chen T, Bedford MT, Dent SY, Richburg JH, Estevez R, Pan HL, Geha RS,Shi Q , Benavides F*Deficient LRRC8A-dependent volume-regulated anion channel activity is associated with male infertility in mice. JCI insight 2018;3(16).
33.AbuMadighem A, Solomon R, Stepanovsky A, Kapelushnik J, Shi Q, Meese E, Lunenfeld E, Huleihel M*. Development of Spermatogenesis In Vitro in Three-Dimensional Culture from Spermatogonial Cells of Busulfan-Treated Immature Mice. Int J Mol Sci . 33.Int J Mol Sci 2018;19(12).
34. Abofoul-Azab M, AbuMadighem A, Lunenfeld E, Kapelushnik J, Shi Q, Pinkas H, Huleihel M*. Development of Postmeiotic Cells In Vitro from Spermatogonial Cells of Prepubertal Cancer Patients.  Stem Cells Dev 2018;27(15):1007-20.
35. Shi B, Xue J, Zhou J, Kasowitz SD, Zhang Y, Liang G, Guan Y, Shi Q,Liu M, Sha J, Huang X*, Wang PJ*MORC2B is essential for meiotic progression and fertility.  PLoS Genet 2018;14(1):e1007175.
36.Jiang L, Li T, Zhang X, Zhang B, Yu C, Li Y, Fan S, Jiang X, Khan T, Hao Q, Xu P, Nadano D, Huleihel M, Lunenfeld E, Wang PJ, Zhang Y*, Shi Q*. RPL10L Is Required for Male Meiotic Division by Compensating for RPL10 during Meiotic Sex Chromosome Inactivation in Mice Curr Biol. 2017 27(10):1498-1505.
37. Yin S, Jiang X, Jiang H, Gao Q, Wang F, Fan S, Khan T, Jabeen N, Khan M, Ali A, Xu P, Pandita TK, Fan HY, Zhang Y, Shi Q*. Histone acetyltransferase KAT8 is essential for mouse oocyte development by regulating ROS levels. Development. 37.2017 144(12): 2165-2174.
39. Pan H, Zhang X, Jiang H, Jiang X, Wang L, Qi Q, Bi Y, Wang J, Shi Q*, Li R*. Ndrg3 gene regulates DSB repair during meiosis through modulation the ERK signal pathway in the male germ cells. Sci Rep. 2017 Mar 14;7:44440. doi: 10.1038/srep44440.
40. Liu C, Li M, Li T, Zhao H, Huang J, Wang Y, Gao Q, Yu Y*, Shi Q*. ECAT1 is essential for human oocyte maturation and pre-implantation development of the resulting embryos. Sci Rep. 2016 Dec 5;6:38192. doi: 10.1038/srep38192.

41. Zhang Y, Zang Q, Zhang H, Ban R, Yang Y, Iqbal F, Li A*, Shi Q*. DeAnnCNV: a tool for online detection and annotation of copy number variations from whole-exome sequencing data Nucleic Acids Res 44(W1):W166-175, 2016.

42. Zhang Y, Zang Q, Xu B, Zheng W, Ban R, Zhang H, Yang Y, Hao Q, Iqbal F, Li A*, Shi Q*. IsomiR Bank: a research resource for tracking IsomiRs. Bioinformatics 32(13):2069-71. 2016.

43. Zhou Q, Wang M, Yuan Y, Wang X, Fu R, Wan H, Xie M, Liu M, Guo X, Zheng Y, Feng G, Shi Q, Zhao XY*, Sha J*, Zhou Q*. Complete Meiosis from Embryonic Stem Cell-Derived Germ Cells In Vitro. Cell Stem Cell 18(3):330-340. 2016.

44. Wu C, Wang L, Iqbal F, Jiang X, Bukhari I, Guo T, Yin G, Cooke HJ, Cao Z, Jiang H*, Shi Q* Preferential Y-Y pairing and synapsis and abnormal meiotic recombination in a 47,XYY man with non obstructive azoospermia. Mol Cytogenet. 9:9. 2016.

45. Sun R, Sun YC, Ge W, Tan H, Cheng SF, Yin S, Sun XF, Li L, Dyce P, Li J, Yang X, Shi Q* ,Wei Shen* The crucial role of Activin A on the formation of primordial germ cell-like cells from skin-derived stem cells in vitro.  Cell Cycle. 14(19):3016-29 2015.

46. Ge W, Ma HG, Cheng SF, Sun YC, Sun LL, Sun XF, Li L, Dyce P, Li J, Shi Q* , Shen W*. Differentiation of early germ cells from human skin-derived stem cells without exogenous gene integration.  Sci Rep. 5:13822, 2015.

47. Zhang Y, Yu Z, Ban R, Zhang H, Iqbal F, Zhao A, Li A*,Shi Q*. DeAnnCNV: a tool for online detection and annotation of copy number variations from whole-exome sequencing data.  Nucleic Acids Res. 43(W1):W289-94 2015.

48. Chu B, Zhong L, Dou S, Wang J, Li J, Wang M, Shi Q* , Mei Y* , Wu M*. miRNA-181 regulates embryo implantation in mice through targeting leukemia inhibitory factor. Mol Cell Biol 7(1):12-22,2015.

49.Wang L, Xu Z, Iqbal F, Zhong L, Zhang Y, Wu C, Zhou G, Jiang H, Bukhari I, Cooke HJ, Shi Q*. Decreased XY recombination and disturbed meiotic prophase I progression in an infertile 48, XYY, +sSMC man. Chromosome Res 23(2):267-76,2015

50. Jiang X, Ma T, Zhang Y, Zhang H, Yin S, Zheng W, Wang L, Wang Z, Khan M, Sheikh SW, Bukhari I, Iqbal F, Cooke HJ, Shi Q*. Specific Deletion of Cdh2 in Sertoli Cells Leads to Altered Meiotic Progression and Subfertility of Mice. Biology of Reproduction 92(3):1-12,2015

51. Hua J, Xu B, Yang Y, Ban R, Iqbal F, Cooke HJ, Zhang Y*, Shi Q*. Follicle Online: an integrated database of follicle assembly, development and ovulation. Database (Oxford). 2015 Apr 29; 2015:bav036.
52. Wang L, Iqbal F, Li G, Jiang X, Bukhari I, Jiang H, Yang Q, Zhong L, Zhang Y, Hua J, Cooke HJ, Shi Q*. Abnormal meiotic recombination with complex chromosomal rearrangement in an azoospermic man. Reprod Biomed Online. 30(6):651-8,2015.
53. Gao X, Ma W, Nie J, Zhang C, Zhang J, Yao G, Han J, Xu J, Hu B, Du Y, Shi Q,Yang Z, Huang X*,Zhang Y*. A G-quadruplex DNA structure resolvase, RHAU, is essential for spermatogonia differentiation. Cell Death Dis 2015 Jan 22;6:e1610.
54. Wang Z, Yin H, Zhang Y, Feng Y, Yan Z, Jiang X, Bukhari I, Iqbal F, Cooke HJ, Shi Q*. miR-214-mediated downregulation of RNF8 induces chromosomal instability in ovarian cancer cells Cell Cycle 13(2):3519-3528,2014.
55. Jiang X, Zhang H, Yin S, Zhang Y, Yang W, Zheng W, Wang L, Wang Z, Bukhari I, Cooke HJ,Iqbal F*, Shi Q*. Specific deficiency of Plzf paralog, Zbtb20, in Sertoli cells does not affect spermatogenesis and fertility in mice. Sci Rep 4:7062, 2014.
56. Ma H, Cooke HJ, Shi Q*. Meiosis: Recent Progress and New Opportunities J Genet Genomics 41(3):83-5,2014.
57. Jiang H, Wang L, Cui Y, Xu Z, Guo T, Cheng D, Xu P, Yu W, Shi Q*. Meiotic Chromosome Behavior in a Human Male t(8;15) Carrier. J Genet Genomics. 2014, 41(3):177-85. doi: 10.1186/1755-8166-7-45.
58. Yao Q, Wang L, Yao B, Gao H, Li W, Xia X, Shi Q , Cui Y*. Meiotic prophase I defects in an oligospermic man with Wolf-Hirschhorn syndrome with ring chromosome 4. Mol Cytogenet. 2014, 7:45. doi: 10.1186/1755-8166-7-45.
59. Wang J, Qian J, Hu Y, Kong X, Chen H , Shi Q ,Jiang L, Wu C, Zou W, Chen Y, Xu J, Fang JY*. ArhGAP30 promotes p53 acetylation and function in colorectal cancer. Nat Commun. 2014, 5:4735.
60. Jiang XH, Bukhari I, Zheng W, Yin S, Wang Z, Cooke HJ, Shi Q* . Blood-testis barrier and spermatogenesis: lessons from genetically-modified mice Asian J Androl 16(4):572-80,2014
61. Zhang H, Jiang X, Zhang Y, Xu B, Hua J, Ma T, Zheng W, Sun R, Shen W, Cooke HJ, Hao Q, Qiao J, Shi Q*. microRNA 376a regulates follicle assembly by targeting Pcna in fetal and neonatal mouse ovaries hybrid cells Reproduction 148(1):43-54,2014
62. Wang Z, Yin H, Lv L, Feng Y, Chen S, Liang J, Huang Y, Jiang X, Jiang H, Bukhari I, Wu L, Cooke HJ, Shi Q*. Unrepaired DNA damage facilitates elimination of uniparental chromosomes in interspecific hybrid cells Cell Cycle 13(8):1345-56,2014
63. Yang Q, Hua J, Wang L, Xu B, Zhang H, Ye N, Zhang Z, Yu D, Cooke HJ, Zhang Y, Shi Q *. MicroRNA and piRNA Profiles in Normal Human Testis Detected by Next Generation Sequencing Plos One 8(6):e66809, 2013
64. Wu J, Liu Q, Wang X, Zheng J, Sheng Sun Z, Shi Q*. mirTools 2.0 for non-coding RNA discovery, profiling and functional annotation based on high-throughput sequencing RNA Biol 10(7), 2013
65. Zhang Y, Zhong L, Xu B, Yang Y, Ban R, Zhu J, Cooke HJ, Hao Q, Shi Q*. SpermatogenesisOnline 1.0: a resource for spermatogenesis based on manual literature curation and genome-wide data mining. Nucleic Acids Res 41:D1055-62,2013
66. Wang XX, Ying P, Diao F, Wang Q, Ye D, Jiang C, Shen N, Xu N, Chen WB, Lai SS, Jiang S, Miao XL, Feng J, Tao WW, Zhao NW, Yao B, Xu ZP, Sun HX, Li JM, Sha JH, Huang XX, Shi Q,Tang H, Gao X*,Li CJ*. Altered protein prenylation in Sertoli cells is associated with adult infertility resulting from childhood mumps infection. J Exp Med. 2013, 210(8):1559-74.
67. Lv L, Zhang T, Yi Q, Huang Y, Wang Z, Hou H, Zhang H, Zhang W, Hao Q, Guo Z, Cooke HJ, Shi Q*. Tetraploid cells from cytokinesis failure induce aneuploidy and spontaneous transformation of mouse. Cell Cycle 11(15), 2864-2875, 2012
68. Zhang Y, Xu B, Yang Y, Ban R, Zhang H, Jiang X, Cooke HJ, Xue Y, Shi Q*. CPSS: a computational platform for the analysis of small RNA deep sequencing data. Bioinformatics 28(14):1925-1927, 2012
70. Hou H, Zhang Y, Huang Y, Yi Q, Lv L, Zhang T, Chen D, Hao Q, Shi Q*. Inhibitors of phosphatidylinositol 3'-kinases promote mitotic cell death in HeLa cells. PLoS One 7(4):e35665, 2012
71. Huang Y, Jiang L, Yi Q, Lv L, Wang Z, Zhao X, Zhong L, Jiang H, Rasool S, Hao Q, Guo Z, Cooke HJ, Fenech M, Shi Q*. Lagging chromosomes entrapped in micronuclei are not 'lost' by cells. Cell Res 22(5):932-5, 2012 Feb 21.
72. Pan Z, Yang Q, Ye N, Wang L, Li J, Yu D, Cooke HJ, Shi Q*. Complex relationship between meiotic recombination frequency and autosomal synaptonemal complex length per cell in normal human males. Am J Med Genet A 158A(3):581-7, 2012
73. Chao H, Zhang X, Chen B, Pan B, Zhang L, Li L, Sun X, Shi Q,Shen W*. Bisphenol A exposure modifies methylation of imprinted genes in mouse oocytes via the estrogen receptor signaling pathway. Histochem Cell Biol 2012 137:249-259.
74. Chen D, Zhang Y, Yi Q, Huang Y, Hou H, Zhang Y, Hao Q, Cooke HJ, Li L, Sun Q, Shi Q*. Regulation of Asymmetrical Cytokinesis by cAMP during Meiosis I in Mouse Oocytes.  PLoS One 7(1):e29735, 2012
75. Yi Q, Zhao X, Huang Y, Ma T, Zhang Y, Hou H, Cooke HJ, Yang DQ, Wu M, Shi Q*. p53 dependent centrosome clustering prevents multipolar mitosis in tetraploid cells.  PLoS One 6(11):e27304, 2011
76. Chen Q, Shi X, Rudolph C, Yu Y, Zhang D, Zhao X, Mai S, Wang G, Schlegelberger B, Shi Q*. Recurrent trisomy and Robertsonian translocation of chromosome 14 in murine iPS cell lines.  Chromosome Res 19(7):857-68, 2011
77. Yang Q, Zhang D, Leng M, Yang L, Zhong L, Cooke HJ, Shi Q*. Synapsis and meiotic recombination in male Chinese muntjac (Muntiacus reevesi).  PLoS One 6(4):e19255, 2011
78. Huang Y, Hou H, Yi Q, Zhang Y, Chen D, Jiang E, Xia Y, Fenech M, Shi Q * . The fate of micronucleated cells post X-irradiation detected by live cell imaging.  DNA Repair 10:629-38, 2011
79. Zhang Y, Yang Y, Zhang H, Jiang X, Xu B, Xue Y, Cao Y, Zhai Q, Zhai Y, Xu M, Cooke HJ, Shi Q*. Prediction of novel pre-microRNAs with high accuracy through boosting and SVM.  Bioinformatics 27(10):1436-7, 2011
80. Xu B, Hua J, Zhang Y, Jiang X, Zhang H, Ma T, Zheng W, Sun R, Shen W, Sha J, Cooke HJ, Shi Q*. Proliferating cell nuclear antigen (PCNA) regulates primordial follicle assembly by promoting apoptosis of oocytes in fetal and neonatal mouse ovaries.  PLoS One 6(1):e16046, 2011
81. Huang Y, Shi Q*.Micronucleus formation detected by live-cell imaging.  Mutagenesis 26(1):133-8, 2011
82. Cai X, Li J, Yang Q, Shi Q*. Gamma-irradiation increased meiotic crossovers in mouse spermatocytes.Mutagenesis.26(6):721-7, 2009
83. Xu W, Chen J, Chen H, Diao R, Fok K, Dong J, Sun T, Chen W, Yu M, Zhang X, Tsang L, Lau A, Shi Q, Huang P, Chan H*. Defective CFTR-dependent CREB activation results in impaired spermatogenesis and azoospermia. PLoS One. 2011, 6: e19120.
84. Wang G, Gao X, Huang Y, Yao Z, Shi Q*,Wu M*. Nucleophosmin/B23 inhibits Eg5-mediated microtubule depolymerization by inactivating its ATPase activity. J Biol Chem, 2010, 285:19060-7.
85. Zhang P, Chao H, Sun X, Li L, Shi Q,Shen W*. Murine folliculogenesis in vitro is stage-specifically regulated by insulin via the Akt signaling pathway. Histochem Cell Biol. 2010, 134: 75-82.
86. Sun L, Sun Z, Zhang P, Zhai X, Tang J, Pan Q, Shi Q,Shen W*. Effect of insulin on oogenesis from mouse fetal germ cells in a serum-free 3D culture system. Reprod Biomed Online. 2010, 20: 11-25.
87. Song L, Li J, Liao W, Feng Y, Yu C, Hu L, Kong Q, Xu L, Zhang X, Liu W, Li M, Zhang L, Kang T, Fu L, Huang W, Xia Y, Tsao S, Li M, Band V, Band H, Shi Q, Zeng Y, Zeng M*. The polycomb group protein Bmi-1 represses the tumor suppressor PTEN and induces epithelial-mesenchymal transition in human nasopharyngeal epithelial cells. J Clin Invest 2009, 119:3626-36.
88. Song Y, Chen Q, Zhang Z, Hou H, Zhang D, Shi Q*. Effects of age on segregation of the X and Y chromosomes in cultured lymphocytes from Chinese men. J Genet Genomics. 2009, 36: 467-474.
89. Leng M, Li G, Zhong L, Hou H, Yu D, Shi Q*. Abnormal synapses and recombination in an azoospermic male carrier of a reciprocal translocation t(1;21).Fertil Steril Apr;91(4):1293.e17-22. 2009
90. Song Z, Min L, Pan Q, Shi Q, Shen W*. Maternal imprinting during mouse oocyte growth in vivo and in vitro. Biochem Biophys Res Commun. 2009 387: 800-805.
91. Wang N, Zhang P, Guo X, Xie J, Huo R, Wang F, Chen L, Shen J, Zhou Z, Shi Q, Zhao B, Sha J*. Comparative proteome profile of immature rat ovary during primordial follicle assembly and development.Proteomics 2009, 9: 3425-3434.
92. Dong H, Li L, Song Z, Tang J, Xuc B, Zhai X, Sun L, Zhang P, Li Z, Pan Q, Shi Q*, Shen W*. Premeiotic fetal murine germ cells cultured in vitro form typical oocyte-like cells but do not progress through meiosis. Theriogenology 2009 72: 219–231.
93. Li JH, Leng M, Ma TL, Yu DX, Shi QH*. Cryopreservation has no effect on meiotic recombination and synapsis in testicular tissues. Fertil Steril Apr;91(4 Suppl):1404-7. 2009
94. Rao X, Zhang Y, Yi Q, Hou H, Xu B, Chu L, Huang Y, Zhang W, Fenech M, Shi Q* .Multiple origins of spontaneously arising micronuclei in HeLa cells: direct evidence from long-term live cell imaging. Mutat Res 646(1-2):41-9, 2008
95. Yan X, Cao L, Li Q, Wu Y, Zhang H, Saiyin H, Liu X, Zhang X, Shi Q ,Yu L*. Aurora C is directly associated with Survivin and required for cytokinesis. Genes Cells 2005 10: 617-626
97. Shi Q, Spriggs E, Field L, Rademaker A, Ko E, Barclay L, Martin RH*.Absence of age effect on meiotic recombination between human X and Y chromosomes. Am J Hum Genet 50.2002 71: 254-261.
98. Martin RH, Shi Q*, Field LL. Recombination in the pseudoautosomal region in a 47, XYY male. Hum Genet 2001 109: 143-145.
100. Shi Q, Spriggs E, Field LL, Ko E, Barclay L, Martin RH*.Single sperm typing demonstrates that reduced recombination is associated with the production of aneuploid 24,XY human sperm Am J Med Genet 2001 99: 34-38.
107. Shi Q, Adler ID*. Colcemid and econazole do not show aneugenicity in male mouse germ cells. Mutagenesis 1998 13(4):409-16.
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